Influenza Flashcards

1
Q

three types of infuenza

A

A, B , C

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2
Q

influenza

A

RNA enveloped
Orthomyxovirdae

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3
Q

Surface antigens

A

H- hemagglutnin
N- neuraminidase

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4
Q

how many strains are covered in the yearly influenza vaccine?

A

4 strains

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5
Q

how many clades/Types of influenza are there

A

3 clades

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6
Q

Influenza A

A

ability to create pandemics.
undergoes antigenic shift and antigenic drift.

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7
Q

Influenza B

A

only in humans,
undergoes antigenic. drift

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8
Q

influenza C

A

causes common cold

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9
Q

What does the annual influenza vaccine contain

A

3 does of Type A and 1 does of type B

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10
Q

Hemagglutinin

A

causes red blood cells to clump together

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11
Q

neurominidase

A

enzyme that helps with transmission ( entry/exit)

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12
Q

antigenic shift

A

switching/swapping of strains of nucleotides

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13
Q

antigenic drift

A

point mutation; change in binding of virius

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14
Q

what is antigenic shift most common in?

A

swine (pig) and avian ( bird)

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15
Q

what are the different types of influenza

A

human, avian, and swine

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16
Q

How does swine flu develop

A

from pig being infected with avian and human flu

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17
Q

Incubation for influenza

A

typical is 2 days
-range 1-4 days

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18
Q

communicable

A

1-4 days before the onset of symptoms and about 5 days after the first symptoms

19
Q

peak shedding for flu

A

first 3 days

20
Q

when does the flu subsides

A

usually 5-7th days in adults- can be ten or more days in childern
-about 50% of infected people do not have symptoms but are still contagious

21
Q

Spread of influenza

A

by virus-laden respiratory droplets that are expelled during coughing and sneezing
-range in size from 0.08 to 0.12up

22
Q

what are the modes of transmission for influenza

A

droplets, airborne, contact, indirect

23
Q

where do particles of influenza last longer

A

moist and warm environments
humidity 35%-40%
temp 28C (82F)

24
Q

how long are particles recoverable on hard, non-porous surfaces

A

more than 24 hours

25
Q

how long are particles transferable to hands on hard, non porous surfaces

A

up to 24 hours

26
Q

how long are particles recoverable on cloth, paper, and tissue

A

8-12 hours

27
Q

how long are particles transferable to hands on clothes , paper, and tissue

A

15 minutes

28
Q

the smaller the particle

A

the more sick one will get

29
Q

where does the particle go if it is small

A

lower respiratory tract

30
Q

where does the particle go if it is medium large

A

upper respiratory tract

31
Q

How many hemgglutnin strains are there?

A

13 types

32
Q

how many neuraminidase strains are there

A

9 types

33
Q

1918

A

spanish flu
H1N1

34
Q

1957-58

A

asain flu
H2N2

35
Q

1968

A

hong kong flu
H3N2

36
Q

what helps detemine how viable the particle will be on surfaces

A

size

37
Q

how many people dies in 1918 from influenza worldwide

A

20-40 million

38
Q

how many people died in 19189 from the influenza in the US

A

500,000

39
Q

how many people died from asain flu worldwide

A

over a million

40
Q

how many people died from Asian flu in US

A

about 70,000

41
Q

what did most people do to get rid of the virus

A

gargled salt water

42
Q

what factors need to be considered

A

-age
-carear
-SES
-

43
Q

the mortality rate of the spanish flu epidemic

A

2.5%