Inflammatory Skin Conditions Flashcards

1
Q

What is the go-to treatment for inflammatory skin conditions?

What side effects are associated with it? (skin only)

A

Topical corticosteroids, eg Hydrocortisone.

Hypopigmentation, hypertrichosis, skin atrophy, telangiectasia (reversible), & striae (irreversible).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Name 4 inflammatory skin conditions.

A

Psoriasis

Atopic Dermatitis

Seborrheic Dermatitis

Lichen Planus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the etiology of psoriasis?

Describe the appearance of its lesions.

Where are the lesions distributed?

A

Psoriasis is immune reaction resulting from many possible triggers (trauma, infection, meds)

Papules & plaques which are silvery & scaly. Also, nail pitting.

On extensor surfaces, eg elbows & knees.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Distinguish between the 4 subtypes of psoriasis.

A

Plaque (most common, often chronic)

Guttate (numerous, small lesions from Strep rxn)

Erythrodermic (generalized erythema)

Pustular (erythema, pustules)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are some possible complications of psoriasis?

A

Psoriatic arthritis, increased risk of metabolic syndrome, atherosclerosis.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Besides corticosteroids, how is psoriasis treated?

A

Various other immunosuppressants.

Vitamin D analogs.

Anti-TNFa agents.

**PUVA: **Psoralen + UVA.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the etiology of Atopic Dermatitis?

Who is affected?

What are some disease associations it has?

A

Multifactorial triggers.

Usually in infancy, but may affect adults.

Associated with Ichthyosis Vulgaris, Staph infection, Herpes infefction.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Describe the lesions seen in atopic dermatitis.

A

Erythematous paplues & plaques which may be crusty. Very pruritis, so presents with evidence of scratching and dry skin (xerosis).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How can atopic dermatitis be treated?

A

Topical corticosteroids.

Various immunosuppressants.

Antihistamines.

Narrowband UVB.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the etiology of Seborrheic Dermatitis?

Who is affected?

Describe the lesions found.

A

Poorly understood…

Usually infants, but sometimes adolescents/adults.

Seborrheic, fatty scales of the scalp (cradle-cap) or sebaceous regions.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

How should seborrheic dermatitis be treated?

A

Emollients.

Maybe low-potency topical corticosteroids.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the etiology of Lichen Planus?

Who is affected?

How can it be treated?

A

T-cell expansion; usually idiopathic but sometimes in response to drugs, viruses, or vaccines.

Middle-aged adults.

Topical corticosteroids & antihistamines, maybe other immunosuppressants (MTX, Mycophenolate). NBUVB.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the 6 Ps of Lichen Planus?

Are there any other findings than these lesions?

A

Purple, polygonal, pruritic, planar, papules/plaques.

Reticular white patches, usually in mucosae (“Wickham’s Striae”)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Does psoriasis have a genetic component?

What medication can trigger psoriasis?

A

Yes, about 1/3 of patients have an affected family member.

Beta blockers, lithium, anti-malarials, interferons. Steroid withdrawal.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the Koebner phenomenon?

What is the Auspitz sign?

A

Koebner - Development of psoriatic lesions at injury sites.

Auspitz - Pinpoint bleeding under removed scales (due to papillary extension)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

How many Lichen Planus patients have nail involvement? What occurs?

A

10%; nail plate thinning, longitudinal ridging, pterygium formation (scarring)

17
Q

Distinguish between the two forms of mucosal lichen planus. Where are they found?

A

Usually oral > genital.

Reticulated: Lace-like pattern of small white papules.

Erosive: On gingiva/tongue, painful.

18
Q

Atopic Dermatitis

Describe its distribution.

What name is assigned to infraorbital folds seen here?

A

Atopic Dermatitis

Flexural surfaces, neck & hands.

Dennie-Morgan folds.

19
Q

What is eczema herpeticum?

Does atopic dermatitis of thin skin merit more or less aggressive treatment than that of thick skin?

A

Widespread Herpes simplex infection.

Thin skin = better penetrance and higher SEs >> Use weaker meds.