Bone/Cartilage VM - Cirillo Flashcards
Name 3-4 types of cartilage.
Hyaline
Elastic
Fibrocartilage
Articular*
Why is hyaline cartilage homogeneously staining, while elastic cartilage isn’t?
Why does hyaline cartilage stain blue?
Elastin fibers in the latter cause uneven staining.
It contains highly sulfated (negative) proteoglycans.
What is a cell nest?
A cavity which houses up to 8 dividing chondrocytes.
What type of cartilage is the IV disc made of?
Laryngeal cartilage?
Fibrocartilage.
Elastic cartilage.
What type of cartilage does articular cartilage most resemble?
Hyaline.
Why is fibrocartilage more effective as a shock absorber than hyaline or elastic cartilage?
Collagen is arranged in bundles which resist compression & shear forces.
Describe how mature and developing cartilage will differ in histological appearance.
Developing cartilage will have more cells, and less matrix.
What comprises the majority of the periosteum?
Fibrous connective tissue (remember, many muscles attach to it).
What can be found within a Haversian canal?
Blood vessels, nerves, bone forming cells.
In what kind of bone can you find “spicules”?
Spongy (not cortical) bone.
Why are osteoblasts basophilic?
They contain abundant rRER for matrix synthesis, which is apparently basophilic.
What are the zones of the epiphyseal plate?
Reserve cartilage
Zone of proliferation
Zone of hypertrophy
Zone of calcification
Zone of ossification
Does bone:
Contain cell nests?
Contain blood vessels?
Contain lamellae?
Turn over rapidly?
No cell nests (cartilage yes)
Has blood vessels (cartilage is avascular)
Is lamellar (cartilage no)
Turns over rapidly! (Cartilage slowly)
