Inflammatory rheumatic diseases Flashcards
3 kinds of musculoskeletal pain
Back pain
Arthralgia
Myalgia
Name 3 autoimmune rheumatic diseases
Rheumatoid arthritis
Connective tissue disorder
Spondarthritis
Define monoarthralgia and polyarthralgia
Mono- affects one joint
Poly- many joints
Name 3 conditions that affect one joint
Degenerative disorder
Infection
Crystal arthropathy
What indicates that fibromyalgia is responsible for polyarthralgia
Presence of tender points
What indicates systemic rheumatic disease is the cause of polyarticular pain
Synovitis lasting more than 6 weeks
If there is synovitis lasting <6 weeks what is the diagnosis
Viral arthritis
What is the female: male ratio of RA
3:1
In what % of RA cases are hands and feet affected
> 80% of cases
Name 2 knee problems related to RA
Valgus deformity
Bakers cyst
Name 3 occular complications of RA
Keratoconjuctivitis sicca
Scleritis and episcleritis
Scleromalacia
Name 3 neuromuscular complications of RA
Muscle wastage
Carpal tunnel syndrome
Atlanto-axial subluxation
What cardiac complications may follow RA
Ischaemic heart diseasse (pericarditis, nodule, endocarditis)
What bone complications may follow RA
Accelerated osteoporosis
What is the main auto-antibody seen in RA
Autoantibody against Fc fragment of IgG
What can be detected early in RA via an ultrasound
Synovial thickening
Effusion
Poer doppler signal (red)
Name 6 elements of the classification criteria for RA
Morning stiffness Arthritis of 3 or more joint areas Symmetric arthritis Rheumatoid factor Rheumatoid nodules Characteristic radiological changes
What is a more realistic/ pragmatic diagnosis of RA
Inflammation of 3 or more joints
Rheumatoid factor/ anti CPP
Raised ESR
Name 2 adjunctive therapies used to treat RA
Bisphosphonates
Statins
Name some symptoms of systemic lupus arythematosus
Systemic- low grade fever+ photosensitivity Face- butterfly rash Psychological- fatigue/ loss of appetite Pleura- inflammation Joints- arthritis
What is scleroderma
Immune mediated disease causing hard, thickened skin
What is dermatomyositis
Skin rash and muscle weakness
What does anklylosing spondylitis have a strong association with
HLA B27
Describe onset and duration of ankylosing spondylitis
Onset of back discomfort before age 40
Insidious onset
Duration > 3 months
