Inflammatory response (jove) Flashcards

1
Q

What is the inflammatory response?

A

Is part of the immune system, acting as a localized, nonspecific reaction to injury or infection.

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2
Q

What are the 2 key features of the inflammatory response?

A
  • Localized Reaction
  • Nonspecific:
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3
Q

What is Localized Reaction of the inflammatory response?

A
  • Localized Reaction: Occurs at the site of injury or infection.
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4
Q

What is Nonspecific Reaction of the inflammatory response?

A
  • Nonspecific: Not targeted at a specific pathogen but rather a general response to any damaging stimulus.
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5
Q

What are the 5 symptoms of the inflammatory response?

A
  • Redness: Caused by increased blood flow to the affected area.
  • Swelling: Resulting from the accumulation of fluid in the tissues.
  • Heat: Due to increased blood flow and metabolic activity.
  • Pain: Triggered by inflammatory chemicals that stimulate nerve endings.
  • Loss of Function: May occur in severe cases due to pain and swelling.
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6
Q

What 4 triggers the inflammatory response?

A
  • Physical Damage: Abrasions or cuts.
  • Chemical Irritants: Substances that can cause tissue damage.
  • Pathogens: Bacteria, viruses, or fungi.
  • Extreme Temperatures: Both heat and cold can induce inflammation.
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7
Q

What is the mechanism of the inflammatory response?

A
  1. Injury or Infection: A damaging stimulus occurs.
  2. Chemical Release: Damaged tissues and immune cells secrete inflammatory chemicals.
    • Histamine: Released by mast cells, increases blood vessel dilation and permeability.
    • Prostaglandins: Also released by mast cells, contribute to inflammation and pain.
  3. Vasodilation: Increased blood flow leads to redness and heat.
  4. Increased Permeability: Plasma fluid leaks into tissues, causing swelling and pressure.
  5. Enhanced Immune Activity: Influx of immune cells (phagocytes) to the site of injury to combat pathogens and clear debris.
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8
Q

What is the importance of the inflammatory response? (2)

A

-Accelerates Healing: The inflammatory response helps to clear out pathogens and damaged cells, facilitating tissue repair.
- Boosts Immune Function: Increases the activity of immune cells and enzymes that fight infections.

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9
Q

What is the conclusion about the inflammatory response?

A

The inflammatory response is a vital mechanism that protects the body from harm and initiates healing processes.

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