Inflammatory Bowel Diseases (Foster)

Question 1

What drugs can trigger IBD flares?

Answer 1

NSAIDs and antibiotics

Question 2

What dosage form is best for left-sided/distal UC?

Answer 2

local, PR

Question 3

What dosage form is best for extensive UC?

Answer 3

systemic, PO therapies

Question 4

What dosage form is best for prostitis?

Answer 4

local, PR therapies

Question 5

What are some signs/symptoms of mild-moderate CD?

Answer 5

ambulatory with mainly GI symptoms

Question 6

What are some signs/symptoms of moderate-severe CD?

Answer 6

systemic cysmptoms, or failing therapy with mild-moderate disease

Question 7

What are some signs/symptoms of severe-fulminant CD?

Answer 7

persistent systemic symptoms/tpxocity despite corticosteroids or biologics, presence of cachexia

Question 8

What procedure is generally curative for UC?

Answer 8

proctolectomy

Question 9

Would you recommend surgery for a CD patient?

Answer 9

probably not; risk of recurrence is high

Question 10

Sulfasalazine indication

Answer 10

induction + remission for UC AND CD

Question 11

Sulfasalazine MOA

Answer 11

anti-inflammatory and free-radical scavenging

Question 12

Sulfasalazine ADRs

Answer 12

N/V, headache, anorexia, rash