Inflammatory Bowel Disease (Drugs)

Question 1

Traditional Therapies

Answer 1

• Aminosalicylates
• Corticosteroids
• Immunomodulators
• Antibiotics

Question 2

Targered Response Modifiers

Answer 2

• TNFa Antagonists (2-6 Monthss)
• Alpha-Integrin Therapy (6-10, 10-14 Weeks)
• Interleukin 12/23 Antagonist ()
• Interleukin 23 Antagonist
• JAK Inhibitors
• SP-1 Agonist

Question 3

TNFa Antagonists

Answer 3

• Adalimumab (UC/CD)
• Certolizumab (UC)
• Golimumab (UC)
• Infliximab (UC/CD)

Alpha Cant Go In

Question 4

Alpha-Integrin Therapy

Answer 4

Vedolizumab (UC/CD)

Alpha Vedal Therapy

Question 5

Interleukin 12/23 Antagonist

Answer 5

Ustekinumab (UC/CD) (No ABC)

Question 6

Interleukin 23 Antagonist

Answer 6

• Mirikizumab (UC)
• Risankizumab (CD) (No ABC)

Question 7

JAK Inibitors

Answer 7

• Tofacitinib (UC)
• Upadacitinib (UC/CD)

Question 8

SP-1 Agonist

Answer 8

Ozanimod (UC)

Question 9

Aminosalicyclates

Answer 9

• 5-ASA (UC>CD)
• Sulfasalazine (CD)

Question 10

Corticosteroids

Answer 10

Prednisone (UC/CD)

Question 11

Entocort

Answer 11

Budesonide (CD)

Question 12

Cortiment

Answer 12

Budesonide (UC)

Question 13

Immunomodulators

Answer 13

• Azathioprine, 6-metocaptoprine (UC Induction, UC/CD maintenance)
• Methotrexate (CD)
• Cyclosporine (UC)

Question 14

Antibiotics

Answer 14

• Metronidazole (CD)
• Ciprofloxacin (CD)