Inflammation Flashcards
What is inflammation
What are cardinal signs of inflammation
What are the 5R’s inflammatory steps?
What is histamine synthesised from and metabolised by?
What is histamine released by and what inhibits it?
What are the 4 types of histamine receptors?
What are the effects of stimulation of H1 and H2 receptors?
What are histamines 2 pathological roles?
Describe the triple response
What is histmaines role in gastric acid secretion
What are the therapeutic and side effects of H1 antagonists?
What are the therapeutic and side effects of H2 antagonists?
What are the functions of bradykinin?
What are the pharmacological effects of bradykinin?
Synthesis and metabolism of bradykinase?
Distribution of 5-HT?
What are the inflammatory actions of 5-HT?
Define
Why are eicosanoids important?
Formation of prostanoids?
What are cycloxygenases and what is it attached to
What are the differences between COX-1, COX-2 and COX-3?
What are some classical prostaglandins?
Actions of eicosanoids
Effects of the mediators on bronchospasm?
