Cellular growth regulation Flashcards
1
Q
Define hyperplasia and hypertrophy in relation to cell growth
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2
Q
Growth factors, cytokines and interleukins are proteins that…(3)
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3
Q
What are the 3 broad classes of growth factors, how are they produced/released?
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4
Q
What is the G0 phase of the cell cycle
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5
Q
What do the drugs acting on the cell cycle do?
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6
Q
What is the FACS used for?
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7
Q
What are the 3 cell cycle checkpoints?
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8
Q
Describe the regulation of Cyclin-CDK activity?
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9
Q
What are the 2 families of CKIs?
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10
Q
Describe the sequence of events triggered by growth factors
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11
Q
What happens if DNA damage is detected? (3)
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12
Q
What is TP53 and what is its response in DNA damage?
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