Cell damage and cell death

Question 1

What are some causes of cell damage/death?

Question 2

What is the difference between necrosis and apoptosis?

Question 3

What are the causes of necrosis?

Question 4

Explain the process of necrosis

Question 5

What are the microscopic nuclear, cytoplasmic and biochemical changes of necrosis?

Question 6

What are the microscopic nuclear, cytoplasmic and biochemical changes of apoptosis?

Question 7

What are some clinical investigations associated with cell death?

Question 8

What is the function of necrosis and its 5 different types?

Question 9

What are the functions of apoptosis?

Question 10

What are some examples of apoptosis?

Question 11

What are the factors influencing the balance of life and death at the cellular level?

Question 12

What are the 2 types of apoptosis?

Question 13

What are Caspases, how is it activated and what does it lead to?

Question 14

How do we activate the initiator caspases?

Question 15

Describe the ligand induced dimerisation?

Question 16

Where is cytochrome c released from and when?

Question 17

Describe the intrinsic pathway involving cytochrome c?

Question 18

How is the release of cytochrome c regulated?

Question 19

How do apoptotic and apoptotic proteins work?

Question 20

How does intracellular stress lead to the release of cytochrome C?

Question 21

How does p53 relate to apoptosis?