Inflammation Flashcards
1
Q
when does inflammation occur? (2)
A
when microbes are introduced into normally sterile body sites, or when tissues are damaged
2
Q
what are the four cardinal signs of inflammation? what would the fifth one be?
A
swelling
redness
heat
pain
(loss of function)
3
Q
what causes swelling?
A
accumulation of exudate in tissues.
4
Q
what causes redness?
A
dilation –> increased blood flow –> heat
5
Q
what causes heat?
A
dilation –> increased blood flow –> heat
6
Q
what causes pain?
A
accumulation of exudate in tissues.
also bradykinin secreting prostaglandin which fires nerve endings.
7
Q
what can go wrong in inflammation?
A
sometimes enzymes and toxic products contained within phagocytic cells are inevitably released
8
Q
what are the first phagocytes recruited to the site of infection?
A
neutrophils
