4. Adaptive Immune Response (Chapter 15) Flashcards
name three components of the humoral response
B cells, plasma cells, BCRs
what are B cells?
a type of lymphocyte that makes antibodies
what’s the difference between cell-mediated immunity and humoral immunity?
CMI: deals with invaders residing within a “self” cell, one of the body’s own cells
Humoral: eliminates microbial invaders and toxins that are not within a self cell, in other words, in blood or tissue fluids
where do B cells mature in general? more specifically?
primary lymphoid organs. bone marrow
where do T cells mature in general? more specifically?
primary lymphoid organs. thymus
name the primary lymphoid organs.
function of the primary lymphoid organs?
bone marrow and thymus.
lymphocytes develop here.
what is a lymphocyte?
white blood cells involved in adaptive immunity
ex. B cells and T cells
what are plasma cells? (2)
effector form of a B cell; antibody-secreting factory
what are BCRs?
B-cell receptor.
molecule on a B cell that enables the B cell to recognize a specific antigen.
what cool fact did you learn about BCRs while making these flash cards?
BCR is a membrane-bound derivative of the antibody that the B cell is programmed to make
what does CMI rely on?
T lymphocytes aka T cells!
what are cytotoxic T cells programmed to do?
programmed to destroy infected/cancerous “self” cells
what are helper T cells programmed to do?
programmed to activate B cells, macrophages, and assist other parts of the adaptive immune response
what is a CD marker?
surface molecules that guide the binding of antigen to TCR (T cell receptors)
what is a TCR?
what do they do?
T cell receptor
enable T cells to recognize a specific antigen
