Infective Endocarditis Flashcards

1
Q

What is infective endocarditis?

A
  • Infection of the heart
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2
Q

What structures of the heart can be infected?

A
  • Endocardium
  • Heart valves
  • Intraventricular septum
  • Chordae tendinae
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3
Q

What can inflammation of the valves and heart lead to?

A
  • Heart failure

- Ischaemia

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4
Q

What is meant by infective endocarditis being “not uniform”?

A
  • Various presentations
  • Can depend on underlying cardiac disease
  • Microorganisms involved
  • Complications
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5
Q

Symptoms?

A
  • Fever
  • Fatigue
  • Malaise
  • Chills
  • Arthralgia
  • Weight loss
  • Headache
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6
Q

Signs?

A
  • Pyrexia
  • Congestive heart failure
  • Murmur
  • Vasculitic rash
  • Janeway lesions
  • Roth spots
  • Oslers nodes
  • Nephritis
  • Splinter haemorrhages
  • Clubbing
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7
Q

What is vasculitic rash?

A
  • A rash of the feet

- Non blanching

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8
Q

What are janeway lesions?

A
  • Lesions in the palms and soles

- Non tender

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9
Q

What are roth spots?

A
  • Retinal haemorrages
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10
Q

What are oslers nodes?

A
  • Deep red spots in the fingers

- Painful and raised

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11
Q

Use FROM JANE to remember

A
  • F - Fever
  • R - roth spots
  • O - oslers nodes
  • M - malaise
  • J - janeway lesions
  • A - arthralgia
  • N - nephritis
  • E - embolic phenomena
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12
Q

Risk factors?

A
  • Male
  • Elderly
  • Prosthetic valves
  • Cardiac risk factors
  • IVDA
  • Immunocompromised
  • Diabetes
  • AIDS
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13
Q

Who is more likely to get it and who has a worse prognosis between male and female?

A
  • Males more likely

- Females worse prognosis

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14
Q

Causes?

A
  • Rheumatic fever
  • Valvular disease
  • Gingival disease
  • Congenital heart disease
  • Invasive procedures
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15
Q

Initial blood work?

A
  • FBC (look for neutrophilia)
  • CRP
  • ESR
  • U+E’s (nephritis/infection/sepsis)
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16
Q

What other blood work should be done?

A
  • Blood cultures prior to antibiotics
17
Q

How are the blood cultures performed?

A
  • 3 sets from different sites

- 6 hours between