Aortic Regurgitation Flashcards

1
Q

What does the LV have to accomodate for in aortic regurgitation?

A
  • Systolic volume and regurgitant volume
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2
Q

What does this cause?

A
  • EDV increases
  • Systolic pressure increases
  • Results in left ventricular hypertrophy and LV dilation
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3
Q

What does the LV hypertrophy cause?

A
  • Increased O2 demand
  • Myocardial ischaemia
  • LV failure
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4
Q

What happens if the aortic regurgitation is acute?

A
  • LV doesn’t have time to compensate
  • Wall tension not enough to accomodate
  • Poor prognosis
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5
Q

What happens in chronic aortic regurgitation (symptoms)?

A
  • Long asymptomatic phase

- Dyspnoea oE

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6
Q

Signs?

A
  • Large volume collapsing pulse
  • Wide pulse pressure
  • Hyperdynamic/displaced apex beat
  • Normal S1/S2
  • Early diastolic decrescendo murmur
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7
Q

Causes?

A
  • DILATED AORTA caused by connective tissue disorders or hypertension
  • Leaflet issues
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8
Q

Examples of leaflet issues?

A
  • Bicuspid aortic valve
  • Rheumatic heart disease
  • Endocarditis
  • Myxomatous degeneration
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9
Q

What is myxomatous degeneration?

A

Pathological weakening of connective tissue

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10
Q

Initial investigations?

A
  • ECG
  • CxR
  • Cardiac catheterisation
  • Echocardiogram
  • CMRI
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11
Q

What will be seen on the ECG?

A
  • ST/T changes
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12
Q

What do the ST/T changes suggest?

A
  • LV strain
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13
Q

What will be seen on the CxR?

A
  • Cardiomegaly in chronic AR
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14
Q

What will be evident on the echocardiogram about the AV valve?

A

AV cusp anatomy

  • Thickening
  • Prolapsing
  • Number of cusps
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15
Q

What else will an echocardiogram show besides AV cusp anatomy?

A
  • LV function
  • Hypertrophy
  • Doppler haemodynamic assessment of regurgitant flow
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16
Q

What therapy can be done to delay surgery?

A
  • Vasodilator therapy
17
Q

Surgical option?

A
  • Aortic valve replacement or appendage repair