infective endocarditis 2 Flashcards

1
Q

what are the two most common strep organisms that cause IE

A

Viridans Strep

S. Bovis

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2
Q

what is the treatment for patients over 65 or with native valve IE with no resistance

A

penicillin G
or
Ceftriaxone

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3
Q

what is the duration of therapy for patients over 65 or with native valve IE with no resistance

A

4 weeks

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4
Q

what is the duration of therapy for patients on penicillin G or ceftriaxone plus gentamicin for native valve strep IE

A

2 weeks

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5
Q

who can’t use penicillin G or ceftriaxone plus gentamicin for native valve strep IE

A

pts. with ascess or with a CrCl less than 20

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6
Q

what is recommended when patients are unable to tolerate beta lactam antibiotics with a native valve IE

A

vancomycin

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7
Q

what is the duration of vancomycin for treating a native valve strep IE

A

4 weeks

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8
Q

what is the recommended treatment for patients with a native valve strep IE and is penicillin intermediate/ resistant and durations?

A

still can use penicillin G or ceftriaxone for 4 weeks
plus gentamicin therapy for 2 weeks
OR
4 weeks of Vancomycin

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9
Q

what is recommended for PCN susceptible patients strep IE and a prosthetic valve and for what duration?

A

penicillin G or ceftriaxone for 6 weeks

with or without gentamicin for 2 weeks

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10
Q

what is recommended for PCN susceptible patients strep IE and a prosthetic valve unable to tolerate beta lactam antibiotics and for what duration?

A

vancomycin for 6 weeks

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11
Q

what is recommended for PCN intermediate/ resistant patients strep IE and a prosthetic valve unable to tolerate beta lactam antibiotics and for what duration?

A

vancomycin for 6 weeks

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12
Q

what is recommended for PCN intermediate/ resistant patients strep IE and a prosthetic valve and for what duration?

A

penicillin G or ceftriaxone for 6 weeks
PLUS
Gentamicin for 6 weeks
(vanc monotherapy is preferred)

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13
Q

what is the recommended treatment for patients with a native valve, oxacillin susceptible staph IE and duration

A

nafcillin for 6 weeks

with or without gentamicin for 3-5 days

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14
Q

what is the recommended treatment for patients with a native valve, oxacillin susceptible staph IE and duration for penicillin allergic patients

A

cefazolin for 6 weeks
with or without gentamicin for 3-5 days
(vancomycin is preferred)

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15
Q

what is the recommended treatment for patients with a native valve, oxacillin resistant staph IE and duration

A

vancomycin for 6 weeks

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16
Q

what is the alternative treatment for patients with a native valve, oxacillin resistant staph IE and duration

A

daptomycin

17
Q

what is another name for oxacillin resistant staph strains

A

MRSA

18
Q

what is another naim for oxacillin susceptible staph

A

MSSA

19
Q

what is native valve staph IE treatment is avoided if a patient has a anaphylaxis reaction to penicillin

A

cefazolin

go with vanc

20
Q

what is the recommended treatment for patients with a prosthetic valve, oxacillin susceptible staph IE and duration

A
nafcillin or oxacillin for 6 weeks or longer
PLUS
Rifampin for 6 weeks or longer
PLUS
Gentamicin for 2 weeks
21
Q

what is the recommended treatment for patients with a prosthetic valve, oxacillin resistant staph IE and duration

A
vancomycin for 6 weeks or longer
PLUS
Rifampin for 6 weeks or longer
PLUS
Gentamicin for 2 weeks
22
Q

what is the only condition where vancomycin is used in combination with gentamicin

A

oxacillin resistant staph (MRSA) IE in a prosthetic valve