infective endocarditis 2 Flashcards
what are the two most common strep organisms that cause IE
Viridans Strep
S. Bovis
what is the treatment for patients over 65 or with native valve IE with no resistance
penicillin G
or
Ceftriaxone
what is the duration of therapy for patients over 65 or with native valve IE with no resistance
4 weeks
what is the duration of therapy for patients on penicillin G or ceftriaxone plus gentamicin for native valve strep IE
2 weeks
who can’t use penicillin G or ceftriaxone plus gentamicin for native valve strep IE
pts. with ascess or with a CrCl less than 20
what is recommended when patients are unable to tolerate beta lactam antibiotics with a native valve IE
vancomycin
what is the duration of vancomycin for treating a native valve strep IE
4 weeks
what is the recommended treatment for patients with a native valve strep IE and is penicillin intermediate/ resistant and durations?
still can use penicillin G or ceftriaxone for 4 weeks
plus gentamicin therapy for 2 weeks
OR
4 weeks of Vancomycin
what is recommended for PCN susceptible patients strep IE and a prosthetic valve and for what duration?
penicillin G or ceftriaxone for 6 weeks
with or without gentamicin for 2 weeks
what is recommended for PCN susceptible patients strep IE and a prosthetic valve unable to tolerate beta lactam antibiotics and for what duration?
vancomycin for 6 weeks
what is recommended for PCN intermediate/ resistant patients strep IE and a prosthetic valve unable to tolerate beta lactam antibiotics and for what duration?
vancomycin for 6 weeks
what is recommended for PCN intermediate/ resistant patients strep IE and a prosthetic valve and for what duration?
penicillin G or ceftriaxone for 6 weeks
PLUS
Gentamicin for 6 weeks
(vanc monotherapy is preferred)
what is the recommended treatment for patients with a native valve, oxacillin susceptible staph IE and duration
nafcillin for 6 weeks
with or without gentamicin for 3-5 days
what is the recommended treatment for patients with a native valve, oxacillin susceptible staph IE and duration for penicillin allergic patients
cefazolin for 6 weeks
with or without gentamicin for 3-5 days
(vancomycin is preferred)
what is the recommended treatment for patients with a native valve, oxacillin resistant staph IE and duration
vancomycin for 6 weeks