Infective Colitis Flashcards

1
Q

What does colitis refer to.

A

Inflammation of the colon.

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2
Q

What are the subtypes of colitis. (6)

A
Autoimmune. 
Idiopathic. 
Iatrogenic. 
Vascular disease. 
Infectious. 
Unclassified colitides.
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3
Q

What are some symptoms of colitis. (8)

A
Abdominal pain. 
Bloody diarrhoea. 
Fatigue. 
Anorexia. 
Weight loss. 
Shortness of breath. 
Tachycardia. 
Fever.
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4
Q

What are some extraintestinal symptoms of colitis. (4)

A

Arthritis.
Apathous ulcers.
Painful, erythematous skin.
Red eyes.

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5
Q

What is a common cause of infective colitis.

A

Clostridium difficile.

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6
Q

What is infective colitis caused by clostridium difficile often referred as.

A

Pseudomembranous colitis.

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7
Q

What are some other causative organisms of infective colitis. (2)

A

Shigella.

E.coli (O157:H7).

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8
Q

What parasitic infections can cause infective colitis.

A

Entamoeba histolytica.

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9
Q

When might pseudomembranous colitis occur.

A

After the use of antibiotics.

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10
Q

What sort of bacteria is clostridium difficile. (4)

A

Gram positive.
Anaerobic.
Spore forming.
Bacillus.

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11
Q

What percentage of the population have clostridium difficile as part of their normal gut flora.

A

3-5%.

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12
Q

What percentage of hospitalised patients have clostridium difficile as part of their normal gut flora.

A

Up to 20%.

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13
Q

Who does pseudomembranous colitis affect the most.

A

The elderly.

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14
Q

What complications can pseudomembranous colitis cause in the elderly. (2)

A

Intractable diarrhoea.

This can lead to toxic megacolon and death.

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15
Q

What are indicators of severe disease in pseudomembranous colitis. (5)

A
Temp > 38.5. 
WCC>15. 
Creatinine >50% above baseline. 
Raised lactate. 
Severe abdominal pain.
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16
Q

How is clostridium causing colitis detected.

A

By detecting A or B toxin in the stools by ELISA or PCR.