Gastritis Flashcards
What are some causes og gastritis. (9)
Alcohol. NSAIDs. H.pylori. Reflux/hiatus hernia. Atrophic gastritis. Granulomas (Crohn's, sarcoidosis). CMV. Zollinger-Ellison disease. Menetreier's disease.
What is the typical presentation of gastritis. (3)
Epigastric pain.
Vomiting.
Haematemesis.
How is gastritis diagnosed.
Endoscopy and biopsies.
How is gastritis prevented.
Give PPIs with NSAIDs.
This will prevent bleeding from acute stress ulcers/gastritis so often seen with ill patients on ITU.
How is gastritis treated. (4)
Ranitidine or PPI treatment.
Eradication of H.pylori (triple therapy).
Troxipide 100mg/8h PO improves gastric mucus.
Endoscopic cautery may be needed.
What is gastritis.
It indicated inflammation associated with mucosal injury.
What does gastropathy mean.
Epithelial cell damage and regeneration without inflammation.
What is the commonest cause of gastritis.
H. pylori infection (80%).
How many cases of gastritis are due to autoimmune gastritis.
5%.
What is autoimmune gastritis.
This affects the fundus and body of the stomach, leading to atrophic gastritis and loss of parietal cells with achlorhydria and IF deficiency.
What clinical syndrome can be caused by autoimmune gastritis.
Pernicious anaemia.
What is Menetrier’s disease.
It is a rare condition with characteristic giant gastric folds, mainly in the fundus and the body of the stomach.
What is seen histologically in Menetrer’s disease. (3)
Atrophy of the glands.
Hyperplasia of the gastric pits.
Overall increase in mucosal thickness.
What is the prevalence of H.pylori infection in developed countries.
20-50%.
What is the prevalence of H. pylori infection in developing countries.
80-90%.
