Infectious diseases Flashcards

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1
Q

sources of bacteraemia

A
skin - cellulitis, wound, ulcer
bone - osteomyelitis
prosthesis 
IE 
Septic arthritis
discitis 
septic emboli 
pneumonia
indwelling lines
UTI
IVDU
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2
Q

what is the sepsis 6 protocol

A
O2 
fluids 
antibiotics 
cultures - blood, urine, prosthesis, wound, bone 
urine output 
lactate
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3
Q

what imaging should be done for bacteraemia

A

TTE followed by TOE if abnormal

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4
Q

antibiotic regimen for bacteraemia

A

2 weeks IV flucloxacillin/vancomycin

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5
Q

antibiotic regimen duration for osteomyelitis

A

4 weeks

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6
Q

antibiotic regimen for IE

A

4 weeks

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7
Q

RF for IE

A

abnormal heart valves - calcification, prosthetic, CHD, post rheumatic fever
IVDU
indwelling lines
dental treatment

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8
Q

organisms causing native valve IE

A

staph aureus
viridans strep
enterococcus
staph epi

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9
Q

what is the name of the criteria used for IE

A

Dukes criteria

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10
Q

work up of investigations for IE

A

blood cultures
TTE
TOE

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11
Q

Gm + cocci in clusters

A

staph

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12
Q

Gm + cocci in chains

A

strep

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13
Q

staph epi is a skin contaminant

A

yes

but can also infect prosthetic material

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14
Q

other skin contaminant

A

corynebacterium

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15
Q

presenting symptoms of acute IE

A

sepsis and heart failure

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16
Q

presenting features of subacute IE

A
weight loss 
night sweats 
malaise 
tiredness 
SOB
17
Q

signs of subacute IE

A
fever 
new murmur
finger clubbing 
splinter haemorrhages 
splenomegaly 
Roth spots - eyes 
Janeway lesions - hands
Oslers nodes - 'ouch' hands
microscopic haematuria
18
Q

where are IVDU more likely to get IE

A

tricuspid valve (RHS)

19
Q

colonisation

A

presence of microbe with no inflammation

20
Q

infection

A

inflammation due to microbe

21
Q

bacteraemia

A

presence of viable bacteria in the bloodstream

22
Q

sepsis

A

dysregulated host response to infection

life threatening organ dysfunction

23
Q

criteria for septic shock

A

sepsis AND
persistent hypotension
lactate >2
failure with fluid resuscitation

24
Q

pathogen

A

any bug that has the potential to cause disease

25
Q

Gm + have thick/thin peptidoglycan wall

A

thick