Haematology Flashcards
1
Q
what is used to monitor warfarin use
A
INR
international normalised ratio
2
Q
what is the INR
A
measurement of how long it takes blood to form a clot
3
Q
what is the calculation for INR
A
Prothrombin test / prothrombin control ISI
4
Q
a high INR means the blood is too thin/thick
A
thin - more prone to bleeding
5
Q
a low INR means the blood is too thin/thick
A
thick - more prone to clotting
6
Q
what antibiotics may interact with warfarin
A
macrolides
7
Q
warfarin is teratogenic?
A
yes!
need to warn young patients about this
8
Q
what can you give to reverse warfarin
A
oral vit K
prothrombin complex for severe/life threatening bleeding
9
Q
above which level of INR would you stop warfarin and when would you restart
A
> 8
restart warfarin when INR <5
10
Q
causes of megaloblastic anaemia
A
B12 deficiency pernicious anaemia folate deficiency drugs alcoholism liver disease hypothyroidism myelodysplasia
