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Paeds Exam Cram > Infectious Diseases > Flashcards

Infectious Diseases Flashcards

1
Q

Gram positive cocci

GP stains purple

A 
Staphylococci
- Staph aureaus
- Staph epidermidis
- Staph saphrophyticus
- Coagulase negative staph
Streptococci
- Group A strep: Strep pyogenes, B haemolytic strep
- Group B strep: Strep agalactiae
- Group D strep: Enterococcus faecalis
- Strep viridians
- Strep pneumonia (alpha haemolytic)
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2
Q

Gram positive rods/bacilli

GP stains purple

A

Diptheria
Listeria
Clostridia
Mycobacteria

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3
Q

Gram negative cocci

GN stains pink

A

Neisseria gonnococcus

Neisseria meningitides

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4
Q

Gram negative rods/bacilli

GN stains pink

A 
Enterobacteria
- E. coli
- Salmonella
- Shigella
- Campylobacter
- Cholera
Haemophilus influenza
Pertussis
Pseudomonas
Legionella
Klebsidella
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5
Q

Beta lactams

A 
Penicllin
Cephalosporins
- 1st cefazolin
- 3rd ceftriaxone
- 4th cefepime
Carbapenems
- Imipenum
- Meropenum
Anti-pseudomonals
- Ticarcillin
- Piperacillin
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6
Q

Aminoglycocides

A

Gentamicin
Amikacin
Tobramycin
Streptomycin

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7
Q

Tetracyclines

A

Doxycyline

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8
Q

Macrolides

A

Erythromycin
Azithromycin
Clarithromycin

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9
Q

Fluroquinolones

A

Ciprofloxacin

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10
Q

Glycopeptides

A

Vancomycin

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11
Q

Sufonamides

A

Sulfamethoxazole

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12
Q

Antibiotic mechanism

Cell wall active (inhibit cell wall synthesis)

A

Peptiglycan cross linking: Beta lactams (penicillins, cephalosporins, carbapenems)
Peptidoglycan synthesis: vancomycin

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13
Q

Antibiotic mechanism

Inhibit protein synthesis

A

50S subunit: Macrolides (erythromycin, azithromycin, clarithromycin), choramphenicol, clindamycin
30S subunit: aminoglycosides (gentamicin, amikacin, tobramycin), tetracyclines (doxycycline)

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14
Q

Antibiotic mechanism

Inhibit DNA gyrase

A

Quinolones (ciprofloxacin)

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15
Q

Antibiotic mechanism

Inhibit mRNA synthesis (DNA directed RNA polymerase)

A

Rifampicin

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16
Q

Antibiotic mechanism

Disrupt DNA integrity (via free radicals)

A

Metronidazole

17
Q

Antibiotic mechanism

Inhibit folic acid synthesis (by DNA methylation)

A

Trimethoprim, sulphonamides (sulfamethoxazole)

Paeds Exam Cram (19 decks)

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