Infectious diseases Flashcards
What % of world deaths are due to infectious and parasitic diseases?
26%
Which infectious diseases are the top 3 killers?
- Respiratory infections
- Tuberculosis
- Diarrhea
Define a parasite
Any organism which lives in (endoparasite) or on (ectoparasite) the tissues of a living organism from which it derives its nutrients
How do viruses replicate?
By using the cellular synthetic machinery to direct the synthesis of specialised virions that transfer the viral genome to other cells.
What are the 8 steps in a viral life cycle?
- Adsorpbtion
- Penetration
- Uncoating
- Transcription
- Translation
- Synthesis of virus nucelic acids and the production of virus proteins
- Assembly of new virus particles
- Egress
What are viroids and virusoids?
the smallest known autonomously self-replicating molecules
Viroids - Plant pathogens composed of single-stranded covalently circular RNA molecules (240-375 residues)
Virusoids - satellite RNAs of similar size which are encapsulated by helper viruses
What are prion diseases?
Diseases caused by protein which causes a non-functioning change in shape of a protein which then produces a catalytic process by which more of the protein is made