Infectious diseases Flashcards

1
Q

What is the treatment for PJP pneumonia?

A

Co-trimoxazole

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2
Q

What is the treatment for toxoplasmosis?

A

No treatment if immunocompetent

Pyrimethamine and sulphadiazine are management options for immunocompromised patients.

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3
Q

Bacterial vaginosis involves overgrowth of which bug?

A

Gardnerella vaginalis

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4
Q

With which pneumonia do you see hyponatraemia?

A

legionella

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5
Q

Which bug causes lymes disease?

A

Borrelia burgdorferi

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6
Q

What is Pott’s disease?

A

TB in the vertebrae

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7
Q

How do you diagnose legionella?

A

Urinary antigen test

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8
Q

Which bug causes a chancroid?

A

Haemophilus ducreyi

It is painful and patients with a chancroid caused by ducreyi DO CRY

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9
Q

Which antibiotic in pregnancy for UTI and which one when near term?

A

Nitro

Or cefalexin if near term

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10
Q

What is a chancre Vs a chancroid?

A

Chancre - primary syphillis, painless ulcer

Chancroid - Haemophilus ducreyi, painful ulcer

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11
Q

What is Fitz-Hugh Curtis syndrome?

A

Complication of pelvic inflammatory disease

Liver capsule becomes inflamed causing right upper quadrant pain. This leads to scar tissue formation and peri-hepatic adhesions. It usually occurs in women who have either chlamydia or gonorrhoea.

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12
Q

Which antibiotic for legionella treatment?

A

Macrolides eg clarithromycin

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13
Q

Constipation and ‘rose spots’ points towards which traveller illness?

A

Typhoid

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14
Q

What is the treatment for genital warts?

A

multiple, non-keratinised warts: topical podophyllum
solitary, keratinised warts: cryotherapy

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15
Q

When do you give the tetanus vaccine booster/ immunoglobulin?

A

Five doses is now considered to provide adequate long-term protection against tetanus (this is completed in the routine vaccination schedule). As long as the last dose was <10 years ago then the patient is covered regardless of wound severity.

If last dose > 10 years ago or vaccination status is unknown- reinforcing dose of vaccine required and immunoglobulin if high risk wound.

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16
Q

Leptospirosis is classicaly spread by rat urine, how does it present?

A

Fever
flu-like symptoms
subconjunctival haemorrhage
AKI
hepatitis: jaundice, hepatomegaly
aseptic meningitis

17
Q

How do you investigate and treat leptospirosis?

A

Ix: Serology, PCR, urine/ csf culture

Mx: Benzylpenicillin or doxycycline

18
Q

What is the treatment for bloody diarrhoea and fever?

A

Ciprofloxacin

Most viral or bacterial gastroenteritis do not require treatment.
Clarithromycin is used for traveller’s diarrhoea which is non invasive (no blood or fever)

so eg salmonella - cipro, campylobacter - clari

19
Q

What is the standard test for diagnosing HIV?

A

Combination tests (HIV p24 antigen and HIV antibody)

20
Q

Trimethoprim and co-trimoxazole should not be given to patients on which medication?

A

Methotrexate

21
Q

How long is the course of doxy for lyme’s?

A

21 days

22
Q

What are the live attenuated vaccines that you shouldn’t give to people that are immunocompromised?

A

You Musn’t Prescribe BCG Incase They Suddenly RIP
- Yellow fever (NB high levels of egg, so CI in egg allergic. Yellow like a yolk)
- MMR
- Polio
- BCG
- Influenza
- Typhoid
- Shingles
- Rotavirus

23
Q

What are the TB drug side effects?

A

Rifam-PEE-cin - orange secretions / pee
IsoNERVEzid - peripheral neuropathy
Pyrazinamide - p for pain - gout
Ethambutol - E for eyes (optic neuritis)