Infectious diseases Flashcards

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1
Q

What is an infectious disease?

A

A disease caused by a pathogen, is transmissible, and reduces the effectiveness of the organism’s functions

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2
Q

What is the difference between incidence and prevalence?

A

Incidence is the number of new cases over a certain period, while prevalence is the total number of people with the disease at any given time.

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3
Q

Name the vector for malaria.

A

Female Anopheles mosquito.

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4
Q

How is cholera transmitted?

A

Through the faecal-oral route, often via contaminated water or food.

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5
Q

Why is it difficult to create a vaccine for malaria?

A

Plasmodium is a eukaryote, its antigens differ in different life stages, and it is an intracellular parasite with antigenic concealment.

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6
Q

What causes AIDS and how does it affect the body?

A

AIDS is caused by HIV, which destroys T-helper cells, weakening the immune system and allowing opportunistic infections.

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7
Q

How does penicillin kill bacteria?

A

Penicillin prevents the synthesis of cross-links in bacterial cell walls, leading to wall weakness and eventual bursting.

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7
Q

What are antibiotics and how do they work?

A

Antibiotics kill or stop the growth of bacteria without harming the host. They may interfere with cell walls, proteins, enzymes, DNA, or protein synthesis.

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8
Q

Why don’t antibiotics work against viruses?

A

Viruses lack the cellular structures that antibiotics target, such as cell walls or organelles.

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9
Q

What are some steps to reduce antibiotic resistance?

A
  • complete the full course of antibiotics
  • avoid using them for viral infections
  • rotate antibiotics
  • don’t sell without a prescription.
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10
Q

Why is malaria difficult to control?

A

There is no vaccine, Plasmodium has different life stages with varying antigens, and there is drug and insecticide resistance.

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11
Q

What is a pandemic?

A

A pandemic is a worldwide increase in the number of cases of a particular disease.

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12
Q

How is tuberculosis (TB) transmitted?

A

TB is transmitted through aerosol droplets from an infected person or by consuming contaminated meat or milk.

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13
Q

How is malaria controlled?

A
  • draining stagnant water
  • spraying insecticide
  • using bed nets
  • screening blood before transfusions.
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14
Q

How is HIV transmitted?

A
  • through sexual contact
  • infected blood
  • sharing needles
  • from mother to child during birth or breastfeeding.
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15
Q

What is reverse transcriptase?

A

An enzyme used by retroviruses like HIV to convert viral RNA into DNA in the host cell.

16
Q

How does HIV affect the immune system?

A

HIV destroys T-helper cells, weakening the immune response and leading to opportunistic infections.

17
Q

What is antibiotic resistance, and how does it occur?

A

Resistance occurs when bacteria mutate, survive antibiotic treatments, and pass on the resistant genes to offspring.

18
Q

What is the consequence of antibiotic resistance?

A
  • Increased human illness
  • higher treatment costs
  • longer treatments
  • fewer effective antibiotics.