Infectious Disease Flashcards

1
Q

Tingling/pain then painful blisters on R trunk. Dx?

A

Shingles

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2
Q

List 2 complications of shingles

A

Post-herpetic neuralgia

Ocular disease

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3
Q

What is Tx for shingles?

A

Oral acyclovir

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4
Q

How does shingles Tx differ in immunocompromised pt?

A

High dose IV acyclovir

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5
Q

Painful rash on penis with fever and myalgia. Dx?

A

Herpes

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6
Q

What is Tx for Herpes?

A

Oral acyclovir

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7
Q

Man with purulent urethral discharge. Dysuria. Dx?

A

Gonorrhoea

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8
Q

What are Sx of gonorrhoea in women?

A

Asymptomatic

OR vaginal discharge / pelvic pain / dysuria

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9
Q

What are the usual Sx of chlamydia?

A

Nothing - asymptomatic

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10
Q

Painless hard ulcer on penis. Dx?

A

Primary syphillis

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11
Q

What organism causes primary syphillis?

A

Treponema pallidum

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12
Q

How long does syphillis take to develop from contact?

A

3 weeks

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13
Q

How long does secondary syphillis take to develop?

A

4-8 weeks

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14
Q

What are Sx of secondary syphillis?

A

Lymphadenopathy, malaise, rash

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15
Q

What is Tx of primary syphillis?

A

Procaine penecillin

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16
Q

What kind of ABx is ciprafloxacin?

A

Quinolone

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17
Q

Which type of hepatitis is most common worldwide?

A

Hep A

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18
Q

Fever, malaise, anorexia, nausea. Then jaundice. Dx?

A

Hep A

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19
Q

How are Hep A / B / C transmitted?

A

A = faecal-oral

B and C = IV / sexual

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20
Q

How do Hep C patients present?

A

Chronic - with liver cirrhosis

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21
Q

Fever, headache, vomitting, diarrhoea. Dx?

A

Malaria

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22
Q

What is Tx of Hep A?

A

Conservative - self limiting disease

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23
Q

What is Tx for Hep C?

A

Pegylated Interferon alpha & ribavarin

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24
Q

What is Tx for malaria?

A

Chloroquine

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25
Q

Fever, anorexia, sore throat. Lymphadenopathy. Inflammed tonsils. Dx?

A

EBV

26
Q

List complications of infectious mononucleosis

A

Meningitis
Encephalitis
GBS

27
Q

How is PC of strep sore throat different from EBV?

A

Strep has NO widespread lymphadenopathy

28
Q

What is immediate Mx of bacterial meningitis?

A

1.2mg IM benzylpenicillin

Immediate hospital transfer

29
Q

Koplik spots, fever, cough, coryza. Dx?

A

Measles

30
Q

Parotid swelling w fever, malaise, lethargy. Dx?

A

Mumps

31
Q

What are Koplik spots?

A

Clustered grey lesions in buccal mucosa adjacent to second molar

32
Q

Fever, headache, expanding red rash on thigh. Prev camping trip. Dx?

A

Lyme disease

33
Q

What is Lyme disease?

A

Tick spread infection

34
Q

How do you confirm TB diagnosis?

A

Ziehl-Nielsen Stain

35
Q

Name the 2 main causative organisms of bacterial meningitis

A

Neisseria meningitides

Strep pneumoniae

36
Q

Non blanching rash with meningism Sx. Causative organism?

A

ALWAYS neisseria meningitides

37
Q

Erythematous ulcer on forearm of man who spent few weeks in South America. Dx?

A

Leishmaniasis

38
Q

What transmits Leishmaniasis ?

A

Sand fly

39
Q

What transmits schistosomiasis?

A

Fluke worms in water

40
Q

What confirms the disease of Leishmaniasis?

A

Leishamn-Donovan bodies in bone marrow/spleen/lymph nodes/skin

41
Q

Itchy rash on feet with fever, malaise, myalgia and cough. Dx?

A

Schistosomiasis

42
Q

Features of Schistosomiasis O/E?

A

Hepatosplenomegaly
Fever
Eosinophilia

43
Q

6 week Hx of diarrhoea, abdo pain, nausea and pale stool. Dx?

A

Giardia

44
Q

Tx of giardia?

A

Metronidazole

45
Q

1 week Hx of fever, headache, malaise and cough.
O/E: Patchy maculopapular rash on trunk + splenomegaly. Leukopenia.
Dx?

A

Typhoid

46
Q

Flu like prodrome. Lockjaw. Dx?

A

Tetanus

47
Q

What causes tetanus?

A

Infected wounds - clostridium tetani

48
Q

What is Tx of MRSA?

A

Isolation and IV vancomycin

49
Q

What is the most common causative organism of endocarditis due to dental procedures?

A

Strep viridans

50
Q

What is the most common causative organism of IE in IVDU/prosthetic heart valve its?

A

Staph aureus

51
Q

Itchy rash on web spaces between fingers and toes. Dx?

A

Scabies

52
Q

What is the most common cause of septic arthritis in young men?

A

Neisseria gonorrhoea

53
Q

What is the most common cause of septic arthritis in children?

A

Haemophilius influenzae

54
Q

What is the most common cause of septic arthritis in old men?

A

Staph aureus

55
Q

Dry cough, exertional dyspnoea, fever and malaise. PMH: AIDS. Dx?

A

Pneumocystis jiroveci

56
Q

Fungal infection of oesophagus in HIV+ patient. Organism?

A

Candida albicans

57
Q

Tx of candida albicans?

A

Floconazole

58
Q

What organism causes meningitis in HIV+ patients?

A

Cryptococcus neoformans

59
Q

Pigmented, well defined papules in HIV+ patient. Dx?

A

Kaposi sarcoma

60
Q

What virus is Kaposi’s sarcoma associated with?

A

HHV 8

61
Q

Loss of visual acuity, floaters and headache in HIV+ patient.
Haemorrhages and exudates on fundoscopy.
Dx?

A

CMV retinitis

62
Q

Encephalitis with multiple ring enhancing lesions on CT. PMH: HIV+. Dx?

A

Toxoplasmosis