Infectious Disease Flashcards
Tingling/pain then painful blisters on R trunk. Dx?
Shingles
List 2 complications of shingles
Post-herpetic neuralgia
Ocular disease
What is Tx for shingles?
Oral acyclovir
How does shingles Tx differ in immunocompromised pt?
High dose IV acyclovir
Painful rash on penis with fever and myalgia. Dx?
Herpes
What is Tx for Herpes?
Oral acyclovir
Man with purulent urethral discharge. Dysuria. Dx?
Gonorrhoea
What are Sx of gonorrhoea in women?
Asymptomatic
OR vaginal discharge / pelvic pain / dysuria
What are the usual Sx of chlamydia?
Nothing - asymptomatic
Painless hard ulcer on penis. Dx?
Primary syphillis
What organism causes primary syphillis?
Treponema pallidum
How long does syphillis take to develop from contact?
3 weeks
How long does secondary syphillis take to develop?
4-8 weeks
What are Sx of secondary syphillis?
Lymphadenopathy, malaise, rash
What is Tx of primary syphillis?
Procaine penecillin
What kind of ABx is ciprafloxacin?
Quinolone
Which type of hepatitis is most common worldwide?
Hep A
Fever, malaise, anorexia, nausea. Then jaundice. Dx?
Hep A
How are Hep A / B / C transmitted?
A = faecal-oral
B and C = IV / sexual
How do Hep C patients present?
Chronic - with liver cirrhosis
Fever, headache, vomitting, diarrhoea. Dx?
Malaria
What is Tx of Hep A?
Conservative - self limiting disease
What is Tx for Hep C?
Pegylated Interferon alpha & ribavarin
What is Tx for malaria?
Chloroquine
Fever, anorexia, sore throat. Lymphadenopathy. Inflammed tonsils. Dx?
EBV
List complications of infectious mononucleosis
Meningitis
Encephalitis
GBS
How is PC of strep sore throat different from EBV?
Strep has NO widespread lymphadenopathy
What is immediate Mx of bacterial meningitis?
1.2mg IM benzylpenicillin
Immediate hospital transfer
Koplik spots, fever, cough, coryza. Dx?
Measles
Parotid swelling w fever, malaise, lethargy. Dx?
Mumps
What are Koplik spots?
Clustered grey lesions in buccal mucosa adjacent to second molar
Fever, headache, expanding red rash on thigh. Prev camping trip. Dx?
Lyme disease
What is Lyme disease?
Tick spread infection
How do you confirm TB diagnosis?
Ziehl-Nielsen Stain
Name the 2 main causative organisms of bacterial meningitis
Neisseria meningitides
Strep pneumoniae
Non blanching rash with meningism Sx. Causative organism?
ALWAYS neisseria meningitides
Erythematous ulcer on forearm of man who spent few weeks in South America. Dx?
Leishmaniasis
What transmits Leishmaniasis ?
Sand fly
What transmits schistosomiasis?
Fluke worms in water
What confirms the disease of Leishmaniasis?
Leishamn-Donovan bodies in bone marrow/spleen/lymph nodes/skin
Itchy rash on feet with fever, malaise, myalgia and cough. Dx?
Schistosomiasis
Features of Schistosomiasis O/E?
Hepatosplenomegaly
Fever
Eosinophilia
6 week Hx of diarrhoea, abdo pain, nausea and pale stool. Dx?
Giardia
Tx of giardia?
Metronidazole
1 week Hx of fever, headache, malaise and cough.
O/E: Patchy maculopapular rash on trunk + splenomegaly. Leukopenia.
Dx?
Typhoid
Flu like prodrome. Lockjaw. Dx?
Tetanus
What causes tetanus?
Infected wounds - clostridium tetani
What is Tx of MRSA?
Isolation and IV vancomycin
What is the most common causative organism of endocarditis due to dental procedures?
Strep viridans
What is the most common causative organism of IE in IVDU/prosthetic heart valve its?
Staph aureus
Itchy rash on web spaces between fingers and toes. Dx?
Scabies
What is the most common cause of septic arthritis in young men?
Neisseria gonorrhoea
What is the most common cause of septic arthritis in children?
Haemophilius influenzae
What is the most common cause of septic arthritis in old men?
Staph aureus
Dry cough, exertional dyspnoea, fever and malaise. PMH: AIDS. Dx?
Pneumocystis jiroveci
Fungal infection of oesophagus in HIV+ patient. Organism?
Candida albicans
Tx of candida albicans?
Floconazole
What organism causes meningitis in HIV+ patients?
Cryptococcus neoformans
Pigmented, well defined papules in HIV+ patient. Dx?
Kaposi sarcoma
What virus is Kaposi’s sarcoma associated with?
HHV 8
Loss of visual acuity, floaters and headache in HIV+ patient.
Haemorrhages and exudates on fundoscopy.
Dx?
CMV retinitis
Encephalitis with multiple ring enhancing lesions on CT. PMH: HIV+. Dx?
Toxoplasmosis