Derm Flashcards
What is acanthosis nigricans associated with?
Gastric carcinoma Obesity DM Acromegaly Hodgkins lymphoma Thyroid disease
List 2 drug causes of alopecia
Warfarin and heparin
List causes of hirsuitism
PCOS Adrenal / ovarian tumours Cushings Acromegaly CAH Steroids
What is 1st line Tx for eczema?
Emollients and topical steriods
List causes of onycholysis
Psoriasis Dermatitis Infection (fungal) RA Hypothyroidism Trauma Idiopathic
Where are psoriatic lesions found?
Extensors
What is 1st line Tx for psoriasis?
Topicals eg tar, dithranol, Vit D, steriods
List cells in the epidermis
Keratinocytes
Melanocytes
Langerhans cells
Merkel cells
What are skin appendages?
Structures derived from ecto/mesoderm and housed within skin
Give examples of skin appendages?
hair follicles, sebaceous glands, apocrine sweat glands, eccrine sweat glands, nails
White/red patches of buccal mucosa. Dx?
Oral candidiasis
Tx for oral candidiasis?
Nystatin
Chronic itchy blistering skin is associated with what GIT condition? What is it called?
Coeliacs
Dermatitis Herpetiformis
What is the Mx for dermatitis herpetiformis?
Dapsone (sulphone ABx)
Avoiding gluten based foods
What are the dermatological manifestations of neurofibromatosis type 1?
Cafe au lait spots
Neurofibromas
Axillary freckling
What are the dermatological manifestations of neurofibromatosis type 2?
Cafe au lait spots (less than type 1)
Bilateral vestibular schwannomas
What type of inheritance is neurofibromatosis?
Autosomal dominant
List 3 causes of generalised cutaneous hypo pigmentation
Pheylketonuria
Albinism
Hypopituitarism
List 5 causes of localised cutaneous hypo pigmentation
Vitiligo Pityriasis veriscolor Post inflammation skin conditions Tuberous sclerosis Leprosy
Indolent boils which rapidly expand, break down and leave large, ulcerated painful areas with a characteristic undermined edge. Dx?
Pyoderma gangrenosum
List 3 conditions associated w pyoderma gangrenosum
UC, CD, RA