Infectious disease Flashcards

1
Q

Tx for bites

A

Co-Amox

if penn allergic - Metro + doxy

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2
Q

Abx for uncomplicated CAP

A

Amoxicillin
Doxycycline or clarithromycin in penicillin allergic

add flucloxacillin if staphylococci suspected e.g. In influenza

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3
Q

Abx for HAP

A

Within 5 days of admission: co-amoxiclav or cefuroxime

More than 5 days after admission: piperacillin with tazobactam OR a broad-spectrum cephalosporin (e.g. ceftazidime) OR ciprofloxacin

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4
Q

Abx for acute pyelonephritis

A

Broad-spectrum cephalosporin or quinolone

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5
Q

Abx for impetigo

A

Topical hydrogen peroxide

oral flucloxacillin or erythromycin if widespread

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6
Q

Abx for cellulitis

A

Fluclox (clary/doxy if pen allergic)

If near eyes/nose - Co-amox

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7
Q

Abx for Gonorrhoea

A

IM cef

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8
Q

Abx for Chlamydia

A

Doxy or Azithro

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9
Q

Abx for PID

A

IM ceftriaxone + oral doxycycline + oral metronidazole

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10
Q

Abx for Syphilis

A

Benzathina pen / Doxy / erythro

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11
Q

Abx for Bac Vag

A

PO metro (5-7d) or topical clinda

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12
Q

Abx for campylobacter

A

Clari

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13
Q

Abx for Shigella/Salmonella

A

Cipro

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14
Q

Painful genital ulcers with sharply defined, ragged border. Painful inguinal lymphadenopathy

A

Chancroid

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15
Q

PV/Urethral discharge, dysuria, PV bleeding

A

Chlamydia

Tx = 7d doxy
(if preg - azithro, amox, eythro)

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16
Q

HIV/Immunocomp - watery diarrhoea, abdominal cramps, fever
Ziehl-Neelson stain - red cysts

A

Cryptosporidiosis

Supportive Mx if immunocompetent
If compromised - Nitazoxadine

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17
Q

Sore throat with grey psudomembrane on posterior walkl, bulky cervical lymphadenopathy, cardiac symptoms

A

Diphtheria

Mx - IM penicillin, Anti-toxin

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18
Q

Malignancies associated with EBV

A

Burkitt’s Lymphoma
Hodgekins Lymphoma

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19
Q

Cause of HUS

A

E. Coli O157:H7

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20
Q

Prolonged, non-bloody diarrhoea

A

Giardiasis

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21
Q

Profuse, watery diarrhoea
Severe dehydration resulting in weight loss

22
Q

Acute onset bloody diarrhoea
Vomiting and abdominal pain

23
Q

A flu-like prodrome followed by crampy abdominal pains, fever and diarrhoea which may be bloody

A

Campylobacter

24
Q

Gradual onset bloody diarrhoea, abdominal pain and tenderness which may last for several weeks

A

Amoebiasis

25
Tx for genital warts
multiple, non-keratinised warts - top Podophyllum solitary, keratinised warts - cryotherapy
26
Tx for PCP
Co-Trimoxazole
27
Sore throat, Lymphadenopathy, diarrhoea, maculopapular rash, mouth ulcers, myalgia
HIV seroconversion Dx vie HIV Abs, p24 antigen, combination testing
28
Flu + dry cough, bradycardia, confusion, deranged LFTs
Legionella Pneumonia Qs may hint at air con/ foreign travel Bloods - > hyponatraemia Tx - erythromycin/clarithromycin
29
Fever, flu like illness, subconjunctival redness, AKI, jaundice/hepatomeg Farmer/sewage worker/recent travel
Leptospirosis Tx - doxy/azithro
30
Lyme disease
Borrelia burgdorefi Bulls eye rash = erythema migrans Tx = 14-21d Doxy (or amox)
31
Meningitis CSF - cloudy, low glucose, high protein, WCC 10-5000
Bacterial meningitis
32
Meningitis CSF - clear, Gluc = 60-80% plasma, raised protein, WCC 15-1000
Viral meningitis
33
Meningitis CSF - slightly cloudy CSF, fibrin wen, low gluc, high prot, WCC 30-300
Tuberculosis CSF Ziehl Neelson stain
34
Tx for suspected bacterial meningitis
< 3mo - Cefotaxome + amox 3mo - 50yrs - Cefotaxime (or ceftriaxone) # > 50yrs - Cef + amox
35
Tx for MSRA
Vancomycin Teicoplanin Linezolid
36
Flu like symptoms, dry cough, erythema multiforme/nodosum, painful vesicles on the tympanic membrane
Mycoplasma pneumonia CXR - bilat consolidation Bloods - haemolytic anaemia, thrombocytopenia# Tx = Doxy or ery/clari
37
Feverish prodrome rose-red rash across cheeks after few days, may spread
Parvovirus B19 (slapped cheek syndro/erythema infectosum) NB - no longer infectious once rash appears Sickle cell -> Aplastic crisis
38
Low grade fever, maculopapular rash that starts on face and spreads, subocipiotal/postauricular lymphadenopathy
Rubella Complications; arthritis. encephalitis, myocarditis
39
Fever, urticaria, arthralgia, cough, diarrhoea, swimmers itch, haematuria Recent travel
Schistosomiasis Tx - praziquantel inc risk of bladder cancer
40
Tx for syphilis
IM BenPen (or Doxy)
41
Adverse effects of Doxy
Discolouration of teeth (avoid in <12y) photosensitivity Angioedema Black hairy tongue
42
Offensive yellow/green frothy discharge, vulvovaginitis, pinpoint eythrma on cervix
Trichomonas Vaginalis Tx - PO Metro 5-7d
43
Trimethoprim cautions
Do not give with methotrexate Avoid use in pregnancy NB - Co-trimoxazole contains Trim)
44
Tx for TB
Acute TB; 6 month Rifampicin + Isoniazid (+P) + 2 months Pyrazinamide + Ethambutol Latent TB 3 Months Rifampicin + Isoniazid (+P) OR 6 months Isoniazid (+P)
45
Drug adverse effects TB
Rif - liver enz inducer, orange sec Isoniazid - periph neuropathy - prevented by giving pyridoxine (vit B6) Pyrazinamide - gout Ethambutol - optic neuritis
46
What age is the first dose of MMR normally given
3yrs and 4 mo
47
Sputum colour and pneumonia
Rust coloured - Strep pneu Green - psudonomas, H inf, pneumococcal Red-current-jelly - kleb foul smelling/ bad tasting - anaerobic
48
Recent travel - Pc - hepatosplenomeg, jaundice, fever, low platelets
Malaria
49
Recent travel; Fever, muscle pain, loss of appetite, N/V Slow pulse with elevated temp
Yellow fever
50
Immunocompromised; Cataracts, N/V, sore throat
Toxoplasmosis
51
Recent travel 2w ago, fever, itchy papular rash, cough, wheeze, muscle aches
Schistosomiasis From exposure to water - eg rafting on holiday