Gastro Flashcards
Tx for Achalasia
Balloon dilation
Recurrent/persistent - surgical intervention (heller cardiomyotomy)
If too high risk for surg - intra-sphincteric inj of botox
Besty measurement for acute liver function
Prothrombin time and albumin level
Tx for variceal bleeds
Give terlipressin and prophylactic abx before endoscopy
Band ligation
Propranolol = prophylaxis
Alcohol screening Qs
AUDIT (0-40) - 15+ = dependence
FAST (0-16)
CAGE (2+ = +ve)
ICD-10 (3 or more = +ve)
Metabolic acidosis
Elevated anion gap
Elevated serum ketone levels
Normal or low glucose concentration
Alcoholic ketoacidosis
Tx = infusion of saline & thiamine
Liver sy,pto, GGT elev, AST:ALT = > 2
Alcoholic liver disease
Tx = glucocorticoids
Aminosaliycilates SEs (anti inflam in IBD)
Sulphasalazine - SEs = rashes, oligospermia, lung fibrosis
Mesalazine - agranulocytosis, pancreatitis
Ascites causes
Check SAAG level
SAAG >11 - indicates portal HTN (liver disorder, cardiac failure)
SAAG < 11 - low albumin (nephrotic, malnut), malig, inf
Tx for ascties
Reduce dietary sodium
Spironolactone
Prophylactic abx (give cipro if ascitic protein >15)
Amenorrhoea, fever, hepatitis, jaundice
AI hepatitis
Barrets oesophagus
Sq epi -> col epi
RF = GORD/smoking/obesity
Tx high dose PPI, endoscopic surveilance every 3-5 yr
Bile acid malabs
Pc, Causes, Ix, Tx
Presents w/ steatorrhoea
and Vitamin malabs
Causes - coeliac, cholecystectomy, small int bac overgrowth
Inv - SeHCAT
Tx = bile acid sequestrant (cholestyramine)
Sudden onset severe abdominal pain, ascites (distension), tender hepatomeg
Budd Chiari syndro (hepatic vein thrombosis)
Causes - PRV, thrombophilia, preg. COCP`
Flushing, bronchospasm,, diarrhoea, hypotension
Carcinoid tumour
Ix - urinary 5-HIAA
Tx somatostatin analogue (octreotide)
Tx for C-diff
PO Vanc 10/7
second = PO Fidaxomicin
3rd = PO Vanc +/- IV met
If symptoms recur within 12 w - next option
Complication of coeliac
Anaemia (Fe, B12, Folate)
Hyposplenism
Osteoporosis
subfertility
enteropathy asso T-cell lymphoma
Coeliac Ix
Blooods - IgA TTG, IgA (endomysial ab), anti-gliadin antibody
Endoscopic intestinal biopsy
- villous atrophy, crypt hyperplasia
Weight loss, lethargy, diarrhoea, abdo pain, skin tags
CD
Anywhere but commonly terminal ileum and colon
Extraintestinal ft CD
Asymetrical arthritis
Erythema nodosum
Uveitis, episcleritis
Pyoderma gangrenosum
Tx for CD
Inducing remission - glucocorticoids (second line = 5-ASA (mesalazine))
Maintain remission - stop smoking
Azathioprine or mercaptopurine (check TPMT before both)
2nd line = methotrex
left lower quadrant pain, diarrhoea and fever
Diverticulitis
abdominal pain, bloating and change in bowel habit, lethargy, nausea. bladder symptom
Pain better on defecation
IBS
Bloody diarrhoea, Crampy abdominal pain and weight loss . Faecal urgency and tenesmus
UC
Crampy abdominal pains and diarrhoea. malabsorption, mouth ulcers, perianal disease, intestinal obstruction
CD