Infectious Disease Flashcards
What does an elevation in WBCs indicate?
- infection
- drug-indiced
- leukemia
- stress
What does low WBCs indicate?
viral infection
What are signs/ symptons of infection?
Fever >38 (100.4)
altered mentation
chills/ sweating
congestion
stiff neck
burning with urination
What positive labratory value means possible infection/ pneumonia?
procalcitonin
What lab tests indicate UTI?
- bacteria
- pyuria
- nitrite positive
- leucocyte esterase positive
What are treatments for complicated UTIs?
- bactrim 7-10 d
- cipro 7-10 days
- levaquin 5-10 days
What lab values indicate cellulitis/ osteomylitis?
- elevated ESR
- elevated WBCs
- elevated C-reactive protein
What other conditions can make the ESR and CRP elevated?
RA
lupus
Chron’s
What does treatment of cellulitis depend on?
purulent vs. non-purulent
What are symptoms of meningitis?
- N/V
- fever
- headache/ stiff neck
- light sensitivity
- rash (does not fade when pushed)
What weight is vancomycin dosing based on?
actual body weight
What is a loading dose vs. maintenence dose of vanco?
loading: 25mg/kg
maintenance: 15mg/kg
When should AUC levels be checked for vanco?
before 5th or 6th dose
OR
4th dose if q24h
When should AUC levels be checked if a patient is receiving dialysis?
before dialysis
What is the target AUC for Vanco for most indications?
400-600 mcg x hr/ml