Infectious Disease Flashcards

1
Q

What is a gumma and what form of syphilis is it associated with?

A

a form of granuloma (very rare; responds rapidly to treatment)

associated with tertiary syphilis

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2
Q

How is legionella best diagnosed?

A

urine antigen test

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3
Q

Which antibiotic is indicated in management of severe campylobacter GI infection?

A

clarithromycin

C-larithromaJsyn

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4
Q

Faget’s sign

A

fever with relative bradycardia -> can point towards a diagnosis of typhoid fever

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5
Q

Jarisch-Herxheimer reaction

A

fever, rash, tachycardia after the first dose of antibiotic

can occur in the management of syphilis

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6
Q

What are the neurological features of Lyme disease?

A

facial nerve palsy
radicular pain
meningitis

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7
Q

What cancer does schistosomiasis predispose you to?

A

squamous cell carcinoma of the bladder

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8
Q

1st line antibiotic for syphilis

A

benzylpenicillin (penicillin G)

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9
Q

name of the rash in lyme disease

A

erythema (chronicum) migrans

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10
Q

Name some late features of lyme disease

A

Cardio:
- heart block
- peri/myocarditis

Neurological:
- facial nerve palsy
- radicular pain
- meningitis

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11
Q

When can lyme disease be diagnosed clinically?

A

when erythema migrans is present

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11
Q

tests for lyme disease

A

ELISA for for borrelia burgdorferi is the 1st line test

if -ve, and lyme disease is still suspected within 4w of sx onset:
- repeat ELISA 4-6 w later
- immunoblot test for people who have had sx for 12w or longer

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12
Q

What is the management of lyme disease?

A

oral doxycycline

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13
Q

Management of nasal septum haematomas

A

refer to ENT (SAME DAY) for drainage

if left untreated, this could lead to septal necrosis and a ‘saddle-nose’ deformity

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14
Q

Management of latent TB

A

Options:
- 3 months of isoniazid (with pyridoxine) and rifampicin
- 6 months of isoniazid (with pyridoxine

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15
Q

Do you give prophylactic treatment in tick bites?

A

no

only give doxy if there is a rash/sx

16
Q

first line treatment for cellulitis

A

flucloxacillin

17
Q

What medication is prescribed to close contacts of someone with meningococcal meningitis?

A

ciprofloxacin