Infectious Disease Flashcards
What is a gumma and what form of syphilis is it associated with?
a form of granuloma (very rare; responds rapidly to treatment)
associated with tertiary syphilis
How is legionella best diagnosed?
urine antigen test
Which antibiotic is indicated in management of severe campylobacter GI infection?
clarithromycin
C-larithromaJsyn
Faget’s sign
fever with relative bradycardia -> can point towards a diagnosis of typhoid fever
Jarisch-Herxheimer reaction
fever, rash, tachycardia after the first dose of antibiotic
can occur in the management of syphilis
What are the neurological features of Lyme disease?
facial nerve palsy
radicular pain
meningitis
What cancer does schistosomiasis predispose you to?
squamous cell carcinoma of the bladder
1st line antibiotic for syphilis
benzylpenicillin (penicillin G)
name of the rash in lyme disease
erythema (chronicum) migrans
Name some late features of lyme disease
Cardio:
- heart block
- peri/myocarditis
Neurological:
- facial nerve palsy
- radicular pain
- meningitis
When can lyme disease be diagnosed clinically?
when erythema migrans is present
tests for lyme disease
ELISA for for borrelia burgdorferi is the 1st line test
if -ve, and lyme disease is still suspected within 4w of sx onset:
- repeat ELISA 4-6 w later
- immunoblot test for people who have had sx for 12w or longer
What is the management of lyme disease?
oral doxycycline
Management of nasal septum haematomas
refer to ENT (SAME DAY) for drainage
if left untreated, this could lead to septal necrosis and a ‘saddle-nose’ deformity
Management of latent TB
Options:
- 3 months of isoniazid (with pyridoxine) and rifampicin
- 6 months of isoniazid (with pyridoxine
