Infectious Disease Flashcards
He invented the first microscope and described how cocci, bacilli and spirochetes can be found in rainwater and human excretions.
Anton van Leeuwenhoek
He invented the COMPOUND microscope which is still used today.
Hooke
Get a good look, Hooke
He found that the emergent growth of bacterium in nutrient broths is not due to spontaneous generation but rather to biogenesis, AKA “germ theory”
Louis Pasteur
This theory states that microorganisms were the cause of infectious disease.
“Koch Postulates” by Robert Koch
He transmitted anthrax from sick cows to mice, then demonstrated that he could pass the disease from one mouse to another.
Koch
Considered the father of microbiology
Koch
He discovered anthrax, tuberculosis, and cholera
Koch
Name the 3 criteria for eradication of the AGENT/MICROORGANISM:
- Lack of an animal reservoir; only reservoir is a human host
- Only one causative agent or stereotype
- Short incubation period
Name the 4 factors associated with potential eradication of the HOST/POPULATION:
- Protection or immunity can be demonstrated
- Host cannot be re-infected with the agent
- Host cannot shed the organism once infection resolved
- Public acceptance of the vaccine and other control measures is high
These are the 6 factors associated with which element of potential eradication?
- Ease of dx and tx
- Low prevalence of subclinical disease
- High disease burden and economic impact
- Immunity is long term or lifelong
- _____ cannot be reactivated
- _____ has predictable seasonality
Disease
These are 6 factors associated with ______ required for potential eradication:
- Can confer long-lasted protection in just a few injections
- Minimal handling and storage requirements
- Simple administration
- Can be administered simultaneously w/other vaccines or adapted to childhood vaccine schedules
- Few adverse effects
- Low cost to produce and purchase
Vaccination
The CDC established this center to address emerging infectious diseases
National Center for Emerging and Zoonotic Infectious Diseases
Both Ebola and Zika are from this family of virus
Filoviridae
4/5 of this viruses strains occur in an animal host native to Africa. This disease outbreak occurred in West Africa during 2014-2016.
Ebola
This virus was first discovered in a monkey in Uganda in 1947 and has caused microcephaly birth defects and Guillain-Barre syndrome.
Zika