Infectious Canine Hepatitis Flashcards
1
Q
Condition also know as…
A
Rubarth’s disease
2
Q
Causal agent and incubation period
A
Canine adenovirus-1
5-10 days
3
Q
Transmission (4)
A
Spread through excretions/saliva/blood
Enters body through ingestion/inhalation
Direct/indirect
Shed in urine for up to 1yr post recovery
4
Q
Pathophysiology (3)
A
Initially localised in tonsils and lymph nodes
Damages vascular endothelial cells leading to petechial haemorrhage
Replicated in hepatocytes resulting in damage and organ enlargement
5
Q
Clinical signs (8)
A
Petechial haemorrhage Jaundice Hepatomegaly Pyrexia H+D+ V+ A+ Abdominal pain
6
Q
Diagnosis (6)
A
Hx/cs/exam Haematology Liver profile - ALT/ALKP/bile salts Bleed time test - liver damage leads to reduced fibrinogen or molecules with reduced activity Ultrasound Enzyme-linked immunosorbent assay
