Diabetes Mellitus Type 1 Flashcards
1
Q
Define d.mellitus (general)
A
Chronic disorder of carb metabolism
Due to relative or absolute insulin deficiency or resistance
2
Q
Pathophysiology
A
Destruction/damage to beta cells
Failure to produce sufficient insulin
Glucose remains in blood
Reduces amount reaches cells
3
Q
Who is more commonly affected (3)
A
Middle age dogs
Middle age-geriatric cats
Females
4
Q
General Aetiology (6)
A
May be inherited Breed pre-disposition Autoimmune Environmental factors Inflammation Secondary to another condition
5
Q
Breed pre-disposition (3)
A
Beagles
Dachshunds
Schnauzers
No breed pre-disposition in cats
6
Q
Condition may be secondary to what in dogs
A
Severe pancreatitis
7
Q
Condition may be secondary to what in cats
A
Amyloidosis
8
Q
Clinical signs - initial (7)
A
PUPD Weight loss with increased appetite Glucosuria Dehydration Lethargy Chronic/recurrent infections
9
Q
Clinical signs of not treated (4)
A
V+ D+ Cataracts leading to blindness (dogs) NS dysfunction (cats) - weakness, inability to jump
10
Q
Diagnosis (4)
A
Hx/cs/exam Urinalysis - increase in SG - DS for glucose and ketones Blood glucose curve Serum fructosimine - rules out stress induced hyperglycaemia
