Infections in compromised hosts

Question 1

Burn wounds leave patient susceptible to what bugs?

Answer 1

Skin colonizers! Strep and Staph

Question 2

Surgical wound sites are susceptible to..?

Answer 2

Staph aureus

Question 3

Intravascuclar catheters are often colonized by?

Answer 3

Staph epidermidis! grow as biofilm, hide from antibiotics!

Question 4

Natural passage obstructions are often infected by?

Answer 4

oropharyngeal aerobic and anaerobic microflora

Question 5

The most common bacteria to lethally infect neutropenic patients is…

Answer 5

pseudomonas aeruginosa

MEDICAL EMERGENCY! don’t empirically treat for g+s (with vancomycin) because pathogens are low virulence compared to -

Question 6

Persistent fever over 5 days in neutropenic hosts is most likely due to…?

Answer 6

Most likely candida, less likely aspergillus

Question 7

hallmarks of infection

Answer 7

may be absent!! because no neutrophils! no inflammation

Question 8

What is the most important worldwide cause of a secondary defect in adaptive immunity?

Answer 8

Malnutrition

Question 9

Most dangerous in humoral immune impairment?

Answer 9

Bacterial with capsules. ex: S pneumo,H influ, N. Meningitidis. treat empirically! narrow range!

Question 10

Most dangerous in cellular immune impairment?

Answer 10

HUGE VARIETY of microrganisms! Need a diagnosis!