Infections Flashcards
WHAT IS KAWASAKI
A SYSTEMIC VASCULITIS
WHO IS COMMONLY AFFECTED BY KAWASAKI
CHILDREN AGED 4M-6Y
WHAT IS THE PRESENTATION OF KAWASAKI
WEEK ONE
- FEVER LASTING 5 DAYS
- CONJUNCTIVITIS
- STRAWBERRY TONGUE AND CRACKED LIPS
- CERVIACLE LYMPHADENOPATHY
- POLYMORPHUS RASH
WEEK 2-4
- RED OEDEMATUS PALMS AND SOLES THAN THEN CAUSES PEELING OF SKIN ON DIGITS
WEEK 3-8
- CARDIOVASULAR SIGNS
HOW DO YOU DIAGNOSE KAWASAKI
FEVER LASTING 5 DAYS PLUS 4 OTHER SYMPTOMS
BLOODS:
RAISED ESR, CRP, PLATELETS
ECHO AT WEEKS 6+8 TO ASSESS CARDIAC INVOLVEMENT
WHAT IS THE CARDIOVASCULAR RISK ASSOCIATED WITH KAWASAKI
CORONARY ANEURISM
HOW DO YOU TREAT KAWASAKI
IvIg x10D
ASPRIN
CLOPIDROGEL (ANTIPLATELET)
INFLIXIMAB IF THERES PERSISTENT FEVER
WHAT WOULD THE CARDIAC SIGNS OF KAWASAKI BE
GALLOP RYTHUMN
MYOCARDITIS
PERICARDITIS
CORONARY AND PERIFERAL ANEURISMS
HOW DO YOU MANAGE A GIANT CELL ANURISM
WARFRIN AND FOLLOW UP
WHAT CELLS DOES HIV AFFECT
MACROPHAGES
DESRIBE HOW MOTHER CHILD HIV TRANSMISSION OCCURS
AT BIRTH
BREAST FEEDING
EN UTERO
HOW DO YOU DIAGNOSE HIV IN A CHILD
DNA PCR IN A CHILD OVER 18M
BEFORE 18 MONTHS THEN YOU CAN ONLY ASSESS FOR NEGATIVE DIAGNOSIS
- COMPLETION OF ANTENATAL ANTIVIRALS
- X2 NEGATIVE PCR
- X1 PCR AFTER 18 MONTHS
WHY CANT YOU REALLY DIAGNOSE A CHILD WITH HIV BEFORE 18M
MATERNAL ANTIBODIES STILL ARE PRESENT
IF UNTREATED WHEN DOES CHILD HIV TURN TO AIDS
VARYING FROM 1Y +
WHAT ARE MILD PRESENTATIONS OF HIV
LYMPHADENOPATHY
PAROTITIS
WHAT ARE MODERATE PRESENTATIONS OF HIV
RECURRENT BACTERIAL INFECTIONS
CANDIDIASIS
CHRONIC DIARRHOEA
LYMPHOCYTIC INTERSTITIAL PNEUMONITIS
WHAT ARE SEVERE PRESENTATIONS OF HIV
OPPORTUNISTIC INFECTIONS
SEVERE FAILURE TO THRIVE
ENCEPHALOPATHY
MALIGNANY
WHAT IS THE TREATEMENT FOR HIV AIDS IF CD4 IS 200-350
2 NEUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS
1 NON NEUCLOSIDE REVERSE TRANSCRIPTASE INHIBITORS
WHAT IS THE TREAMENT FOR HIV AIDS OF CD4 >350
2 NEUCLOSIDE REVERSE TRANSCRIPTASE INHIBITORS
1 PROTEASE INHIBITORS
WHAT IS ALWAYS GIVEN TO HIV PATIENTS
PCP (CO-TRIMOXAZOLE) IF OVER AGE OF 4
ALL VACCIENES BUT NOT BCG
WHAT ARE GENERAL SIGNS OF A HIV CHILD ON PRESENTATION
PERSISTENT LYMPHADENOPATHY
HEPATOSPLENOMEGALY
RECURRANT FEVER
THROMBOCYTOPENIA
HOW DO YOU REDUCE THE RISK OF VERTICAL TRANSMISSION IN HIV
ANTIRETROVIRAL DRUGS IN PREGNANCY // BEFORE
NOT BREAST FEEDING
AVOIDING PROLONGED ROM
NO INSTRUMENTAL DELIVARIES
WHAT IS ENCEPHALITIS
INFLAMMATION OF THE BRAIN
WHAT ARE CAUSES OF ENCEPHALITIS
MAINLY VIRAL
- HSV
- ENTEROVIRUS (MOST COMMON)
- POST INFECTIOS TO CHICKEN POX AND MEASLES
- HIV
WHAT IS THE PRESENTATION OF ENCEPHALITIS
FEAVER
HEADACHE
DECREASED CONCIOUSNESS
HOW DO YOU DIAGNOSE ENCEPHALITIS
BLOOD CULTURES
SWABS (SKIN AND THROAT)
LP
IMAGING
WHAT IS THE COMMON ISSUE FACED WHEN DIAGNOSING ENCEPHALITIS
ORGANSIM CAN ONLY BE FOUND IN 50% OF CASES
WHAT IS THE MANAGEMENT OF ENCEPHALITIS
TREAT AS MENINGITIS/HSV ENCEPHALITIS UNTIL PROVEN OTHERWISE THEN
SUPPORTIVE UNLESS HSV ENCEPHALITIS
THEN USE ACYCLOVIR
+- PHENYTOIN (ANTICONVUSLANT)
WHAT IS MENINGITIS
INFLAMMATION OF THE MENINGES
USUALLY DUE TO BACTERIA:
PRECEEDED BY BACTEREMIA CAUSING A SEVERE IMMUNE RESPONSE
WHAT PATHOGENS USUALLY CAUSE MENINGITIS AT 0-3M
GBS
E COLI
LISTERIA
WHAT PATHOGENS USUALLY CAUSE MENINGITIS AFETR 3M
NISSERIA MENINGITIDES
STREP. PNEUMONIA
H. INFUENZA
MININGOCOCCUS (V BAD)
WHAT IS THE PRESENTATION OF MENINGITIS IN AN ONLDER CHILD
FEVER
PHOTOPHOBIA
HYPOTONIA
DROWSINESS
NECK STIFFNESS
SHOCK
SEIZURES
PURPURIC NON BLANCHING RASH
HOW DO YOU INVESTIGATE MENINGITIS
BLOOD CULTURES
BLOOD GLUCOSE
GASSES
COAG SCREEN + LACTATE
MSU
THROAT SWAB
LP
PCR
YOU DO AN LP IN A ?MENINGITIS CHILD THE CSF IS:
- TURBID
- POLYMORPHS
- HIGH PROTEIN
- V. LOW GLUCOSE
WHAT IS THE PATHOGEN TYPE
BACTERIAL
YOU DO AN LP IN A ?MENINGITIS CHILD THE CSF IS:
- CLEAR
- LYMPHOCTURES
- NORMAL PROTEIN
- LOW GLUCOSE
WHAT IS THE PATHOGEN TYPE
VIRAL
YOU DO AN LP IN A ?MENINGITIS CHILD THE CSF IS:
NORMAL (BUT CAN BE TURBID)
- LYMPHOCYTES
- VERY HIGH PROTEIN
- VERY LOW GLUCOSE
WHAT IS THE PATHOGEN TYPE
TB
WHAT IS THE MANAGEMENT OF MENINGITIS
SUPPORTIVE
ABX
DEXAMETHOSONE BUT NOT IN INFANTS
WHAT ARE THE ABX TO TREAT MENINGITIS
CEFPTAXIME FOR 21DAYS
WHAT IS THE TREATEMENT FOR CHILDREN UNDER 3M WITH MENINGITIS
CEFOTAMINE + AMOXICILLIN FOR 14D
WHEN IS PROFYLAXIS GIVEN TO CLOSE CONTACTS AND WHAT IS THE ABX USED
WHEN THE MENINGITIS IS CAUSED BY NISSERIA MENINGITIDIS OR H INFLUENA
RIFAMPACIN
WHAT ARE THE COMPLICATIONS OF MENINGITIS
DEATH
CEREBRAL INFARCTION
SUBDURAL EFFUSION - H INFLUENZA
HYDROCEPHALUS
CEREBRAL ABCESS
LOCAL VASCULITIS
HEARNING LOSS
WHAT ARE VIRAL CAUSESOF MENINGITIS
ENTEROVIRUS
EBV
ADENOVIRUS
MUMPS
WHAT IS HSV
A COMMON VIRAL INFECTION THAT GOES THROUGH PERIODS OF LATENCY AND LONG TERM PERSISTANCE
WHAT ARE THE TYPES OF HSV
HSV 1 - LIP AND SKIN LESIONS
HSV 2 - GENITAL LESIONS
WHAT IS THE PRESENTATION OF HSV
PAINFUL VISICULAR LESIONS ON GUMS AND LIPS
- GINGIVOSTOMATITIS AT MUCOCUTANEOUS JUNCTIONS
HIGH FEVER AND IRRITABLE CHILD
BLEPHERITIS AND CONJUNCTIVITIS
ENCEPHALITIS/ESEPTIC MENINGITIS
ECZEMA HERPETICUM
HERPETIC WHITLOWS
WHAT COMPLICATIONS OF HSV THAT CAN MANIFEST DURING A PRIMARY/ACUTE ATTACK
ECZEMA HERPATICUM LEADING TO SERIOUS SECONDARY INFECTIONS
CONREAL SCARRING FROM BLEPHERITIS AND CONJUNCTIVITIS
WHAT IS THE TREATEMENT FOR HSV
TOPICAL ACYCLOVIS
IV ACYCLOVIR IN ENCEPHALIIS OR IN IMMUNOCOMPRIMESED
WHAT IS SCOLDED SKIN SYNDROME
A SKIN INFECTION BY STAPHYLOCOCCUS OR GROUP A STREP
WHAT IS THE PATHOPHYSIOLOGY OF SCALDED SKIN SYNDROME
BACTERIA RELEASESUPERTOXINS WHICH CAUSE THE SEPARATION OF EPITHELIAL SKIN THROUGH TO THE GRANSULAR LAYER