Infections Flashcards
Pathogens
The disease causing microbes, often called germs
- infectious diseases result from invasion of the body by microorganisms and multiplication of these microbes, followed by damage to the body
Non-pathogenic
Do not cause disease, many are beneficial
Infection
- replicating bacteria causes inflammation and tissue damage. 10^5 organisms per gram of tissue
- An invasion of the body by organs is that have the potential to cause disease
- process by which an organisms seeks to utilize the host’s resources to multiply, usually at the expense of the host
- systemic or local
Contamination
Non-replicating bacteria that doesn’t cause inflammatory immune response. The organisms are are present but quiet
Colonization
Replicating bacteria that doesn’t cause additional tissue injury or stimulate host immune response. Can delay or benefit healing
S&S systemic
- fever and chills - sweating - malaise - nausea - vomiting - diarrhea - wound drainage - vital sign changes - pain - headache
S&S local
Pain or tenderness - swelling - redness - warmth
Old ppl and infection
- may NOT have fever
- first sign may be confusion
- susceptible due to: thin fragile skin, immune system chagnes, deceased gag reflexes (pneumonia), dehydration (UTI), cognitive changes
Transmission-based precautions
- contact
- airborne
- droplet
- vehicle
- vector borne
Bacteria
Unicellular organisms that dont require living tissue/cell to survive
- injure by invading tissue and releasing exotoxins and endotoxins that cause cell death and degradation of extracellular matrix
- c diff - staph - strep
C diff
Anaerobic - diarrhea in presence of antibiotic exposure - fecal transplant
- fecal-oral transmission
Staph
Most common cause of infection
- need an opening in the skin to invade
- attacks bones, joints, kidneys, lungs, heart
MRSA
Skin to skin
- HAND WASHING
- antibiotic resistance
- chest issues, non-healing wound
- found skin, lungs, bone, and blood
Viruses
Small intracellular parasites that require a living host cell for replication (attaches to cell)
- NOT affected by antibiotics
- DNA take over host and cell functions abnormally
- mutates and spreads
Direct cytopathic effect
RNA viruses which kill from within by disturbing cellular processes or disrupt nucleus/plasma integrity