Infections Flashcards

1
Q

Most common causes of travellers diarrhoea

A

Enterotoxic E. coli
Enteroinvasive E. coli
Enteroaggregate E. coli
Shigella
Salmonella
Campylobacter
Norovirus
Protozoa

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2
Q

Malaria features

A

Plasmodium falciparum causes most severe type
Spread by Anopheles mosquitos
Suspect in fever in returned traveller
Fever, malaise, HA, anorexia, vomiting, myalgia
May need recurrent blood draws for thick and thin films every 6-12 hours for 48 hours to rule it out completely
Can present a month or so after exposure
Should be hospitalised

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3
Q

Dengue features

A

Short incubation period 4-10 days
Spread by Aedes aegypti mosquitos
Fever + influenza like illness OR hemorrhagic complications eg epistaxis, prolonged periods
Diagnosis is clinical + some blood tests avail eg serology or PCR
Supportive treatment only

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4
Q

Typhoid fever features

A

Incubation period 3-60 days
Vaccination 70% successful only
Requires culture to diagnose, serology unhelpful
Fever + GI sx

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5
Q

Rickettsial disease
(usually from tick bites)

A

Fever + HA + myalgia
Rash may be present
Eschar may be present
Include Rocky Mountain Spotted fever, scrub typhus
Treat with doxycycline

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6
Q

Chikungunya/Zika features

A

Fever + arthralgia +/- myalgia + rash
Arthritis is bilateral and involves small joints in hands and feet

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7
Q

Meningitis immediate ABx pre-hospital

A

Neonate <3 months old benpen 50mg/kg
3m to 10yo ceftriaxone 100mg/kg (max 2g)
Adolescent/adult ceftriaxone 2g

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8
Q

Complicating factors of UTIs

A

Male
Catheterisation
Recent instrumentation
Pregnant
Immunosuppressed
Not improved on ABx in community
>3 in a year
?stone
Abnormal renal tract
Suspected pyelonephritis
Prev resistant organism

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9
Q

Common pathogens for encephalitis

A

Herpes simplex
Varicella
Measles
EBV
Toxoplasmosis
Enteroviruses
Adenoviruses

Autoimmune
Paraneoplastic
Acute demyelinating

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10
Q

Take a travel history

A

Where?
When? When returned?
How long?
Rural or urban?
Purpose of visit?
Hotel or family?
Exposures? - animals, activities eg swimming in lakes/SCUBA, mountaineering, caving, sexual, food, ticks/insects
Vaccinations?
Malaria prophylaxis? What? When? As directed? Still?
Travelling companions also unwell?
Ill while away?
PMH/meds etc

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11
Q

Meningitis organisms by age

A

Neonate: GBS, Listeria, E. coli, other gram negatives. HSV, Strep, HIB, Neisseria
Older: Neisseria, HIB, strep

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12
Q

Encephalitis causes

A

Infectious:
HSV (#1)
VZV, adenoviruses, measles, toxoplasmosis, EBV, post-travel mosquito/tick-borne
Non-infectious:
Immunologic eg acute demyelinating encephalitis, auto-immune, paraneoplastics

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