Infection in Malignancy Flashcards
1
Q
supportive measures to prevent infection in cancer patients?
A
prophylaxis growth factors protective environment IV immunoglobulin replacement vaccine
2
Q
3 factors in neutropenic risk?
A
cause of neutropenia
degree of neutropenia
duration of neutropenia
3
Q
what most common fungal infection in immunocompromised patients?
A
candida - aspergillus
4
Q
what contributes risk to fungal infection?
A
monocytopenia and monocyte dysfunction contribute to risk of fungal infections
5
Q
presentation of neutropenic sepsis? (6)
A
fever with no localising signs rigors chest infection skin sepsis - cellulitis UTI septic shock
6
Q
what is the sepsis 6?
A
administer high flow oxygen take blood cultures give appropriate IV antibiotics within 1 hour measure serum lactate conc. IV fluid resuscitation assess/measure urine output
7
Q
management of neutropenic sepsis?
A
resuscitation - ABC
broad spectrum antibiotics
after 72h add antifungal
CT
8
Q
what important viruses should we be aware of?
A
CMV
Adenovirus
EBV
