Hypersensitivity Flashcards
1
Q
what is immediate (type 1) hypersensitivity reactions mediated by?
A
IgE
2
Q
what makes B cells produce IgE?
A
IL-4 secreted by TH2 cells
3
Q
gene of allergies?
A
Filaggrin
4
Q
Type 2 hypersensitivity antibody?
A
IgG or IgM
5
Q
what happens with Rhesus antigen?
A
IgG develops during pregnancy and crosses the placenta and causes haemolytic disease
6
Q
Type 3 hypersensitivity is mediated by?
A
immune complexes
7
Q
Type 4 (delayed) hypersensitivity mediated by?
A
T cells
