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MRCPCH Part 2 > Infection + immunity > Flashcards

Infection + immunity Flashcards

1
Q

Presentation of entamoeba histolytica

A

Bloody diarrhoea
Lower abdominal pain
Hepatomegaly
Microcytic anaemia

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2
Q

Presentation of diphyllobothrium latum

A

Mild intestinal symptoms

Macrocytic megaloblastic anaemia due to B12 deficiency

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3
Q

Presentation of ancylostoma duodenale

A

Chronic blood loss causing anaemia

Few intestinal symptoms

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4
Q

What HIV testing should newborns have?

A

DNA PCR after birth, at 4 weeks, 3 months and 6 months

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5
Q

Requirements for diagnosis of HIV in a neonate

A

2 positive PCRs obtained at different time points

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6
Q

Presentation of rubella

A

Prodromal period with mild coryza
Fever
Lymphadenopathy (esp sub occipital)
Fine, pink maculopapular rash

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7
Q

Presentation of schistosomiasis

A

Itch lasting 2-3 days
Tiredness
Pyrexia
Liver tenderness

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8
Q

Presentation of typhoid

A

10-14 day incubation period
Vague symptoms for first week
Then headache, vomiting, diarrhoea, cough
Rose spots

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9
Q

Testing for C diff

A

Toxin detection in stool sample

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10
Q

Presentation of ataxia telangiectasia

A

Ataxia becomes apparent at age 4
Telangiectasia - first ocular, then cutaneous
Recurrent sinopulmonary infections

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11
Q

Lab tests for ataxia telangiectasia

A

Fragile chromosomes
Low IgA
Raised alpha fetoprotein

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12
Q

Presents with greyish tonsillar pseudomembrane and rapid disease onset

A

Diphtheria

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13
Q

Treatment of diphtheria

A

Antitoxin

Penicillin or erythromycin

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14
Q

Type of bacteria - E coli

A

Gram negative rods

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15
Q

Type of bacteria - strep pneumoniae

A

Gram positive diplococci

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16
Q

Type of bacteria - N meningitides

A

Paired Gram negative cocci

17
Q

Features of congenital CMV

A 
Prematurity + IUGR
Jaundice
Hepatosplenomegaly
Pneumonitis
Sensorineural deafness
Intracranial calcification
18
Q

Presentation of measles

A

Onset of rash (widespread, morbilliform) after 4 days of prodromal illness
Conjunctivitis
Cough

19
Q

Side effects of amphotericin B

A 
Anorexia
D+V
Fevers
Hypokalaemia
Hypomagnesaemia
20
Q

Best antibiotics for mycoplasma pneumonia

A

Clarithromycin

Erythromycin

21
Q

Presentation of mycoplasma pneumonia

A 
Non exudative pharyngitis
Bullous myringitis
Skin rashes
Wheeze
Muscle tenderness, nerve palsies
Lymphadenopathy
Splenomegaly
Conjunctivitis
Positive cold agglutinins
22
Q

Classical triad of Rocky Mountain spotted fever

A

Fever
Headache
Maculopapular rash which begins on the limbs and spreads centrally

23
Q

3 most frequent organisms causing liver abscess

A

Staph aureus
Serratia
Aspergillus

24
Q

Treatments for non gonococcal urethritis

A

Ceftriaxone
Spectinomycin
Ceftibuten

25
Q

Most common causes of burn wound infections

A

Staph aureus
Pseudomonas aeruginosa
Strep pyogenes

26
Q

Which kind of antibodies indicate an active EBV infection?

A

IgM

MRCPCH Part 2 (24 decks)

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