Infection and Tumors Flashcards

1
Q

why is the brain well protected

A

blood brain barrier

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

T/F WBC can acces brain easily

A

no

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

meningitis from

A

bacteria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

who meningitis

A

infants , bad immune, living close (dorms)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

meningitis presentation

A

fever headache
brudzinski sign
focal CNS sign
seizures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

brudzinski sign

A

flex the neck, the hips n knee automatically flex too

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

focal CNS signs

A

cranial nerve palsy

deaf

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

T/F CNS signs will go away once emergency state of meningitis passed

A

might not

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

pathologly meningitis

A

meninges inflamaed

bbb breakdown

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

encephalitis

A

infection of brain and SC

infection of brain parenchyma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

difference meningitis and encephalitis

A

men: infection of meninges
en: infection of brain and SC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

encephalitis presentation

A

headache nasea vomitting
LOC
coma
medial temporal lobe

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

T/F encephalitis can be caused by meningitis

A

yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

T/F you can’t have meningitis and encephalitis

A

false you can

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

medical temporal lobe

A

lets you make new memories

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

primary pathology of encephalitis

A

viral infection (west nile)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

secondary pathology encephalitis

A

secondary to another viral infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

whats encephalitis cause

A

cell necrosis
loss of plasma
scarring

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

does encephalitis happen slow or fast

A

fast hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

management of meningitis and encephalitis

A

URGENT

MRI, EEG
Antibiotic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

children take longer or less time to recover from meningitis and encephalitis

A

longer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

another name mad cow disease

A

prions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

prions

A

infection to motor system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

presentation prions

A

16-30ys

movement disorder/dementia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
pathology for prions
ingestion or via nose
26
time course prions
5-8 years incubation time
27
management of prions
symptom control
28
why we worried about prions
we can't kill these (usually cook n things are ok)
29
Creutzfeld jakod disease
loss of integrity of neural tissue
30
brain infection pt concerns
isolation process inter cranial pressure (positioning) behavioral changes monitering changes/. if infection reoccurs
31
alzheimer and prions similarities
leave amyloids | weak transmissibility
32
types of brain tumours
brain and benign
33
survival rate brain tumours
50%
34
infra tectorial
below brain stem | children
35
sera tectorial
adults
36
neoplasm classifications
intracerebel (primary and metastatic)
37
intra cerebral: primary tumours
neutrons dont prolifferate | caused by glia
38
intra cerebral : metastatic
from breast lung prostate
39
what increases when tumours grow too
edema cranial pressure permeabilty
40
what can tumours impede
CSF
41
compensation while the tumour grows
dec volume of brain tissue dec CSF volume dec cerebral blood volume
42
presentation primary tumours
``` worse cough bend exercise nausea papilledema LOS seizures ```
43
are primary tumours found small or big
big by the time discovered
44
papilledma
swelling of optic disc
45
stages of cancer
0-4
46
stage 0 cancer
cancer where it started
47
stage 1 cancer
cancer is small and hasn't spread
48
stage 2 cancer
cancer has grown but not spread
49
stage 3 cancer
cancer large may have spread to tissue / lymph
50
stage 4 cancer
cancer has spread to at least 1 other body organ
51
secondary or metastis cancers
stage 4 | has spread to atlas 1 other organ
52
primary tumour - gliomas grades
1-3
53
grade 1 gliomas
cancer cells look normal, slowly growing
54
grade 2 gliomas
cells don't look normal, growing quicker than normal
55
grade 3 gliomas
cells really don't look normal and growing quickly
56
risk factor primary tumour
none known (use to think phones)
57
types of gliomas
low grade / benign | malignant
58
low grade / benign tumours
narrow zones of infiltration | clear on images
59
malignant tumours
diffuse zones of infiltration
60
where can malignant tumours be
anywhere in CNS
61
who gets malignant tumours
adults
62
astrocytomas
from astrocyes don't spread outside brain n SC benign or malignant
63
oligodendroglioma
from oligodendoryctes of brain adults often malignant
64
medulloblastomas
highly malignant originated cerebellum / infratentorial rapid growing through CSF
65
low grade astrocytomas (benign)
non malignant progressive slow progress
66
where is low grade astrocytomas in kids and adults
adults cerebrum | children cerebellum
67
anapaestic astrocytoma (malignant)
``` aggressive infiltrative almost always re occur front and temporal lobs poor prognosis ```
68
oligodendroglioma (malignant )
slow solid 50% survive
69
medullobalstoma (malignant)
Veris of cerebellum fast, vascular spread in subarachnoid spade 70% survival
70
signs of intraspinal tumour
root pain - whose at night / cough
71
brain tumour management
image surgery / radiation control cranial pressure, swelling