Infarct CV Remodeling- Sosnowski Flashcards
key risk factor for MI’s
lifestyle choices
inadequate blood supply (decreased delivery of O2 and nutrients) to myocardium causing myocyte death
Myocardial Infarct
chest pain (can radiate)
dyspnea/sob
epigastric discomfort/N/V
diaphoresis
syncope
cognitive dysfunction
signs and symptoms of MI
if heart is not beating well, what will try and compensate for that and ultimately make situation worse
sympathetic nervous system
what do you see on EKG for STEMI
convex ST elevation
what leads will have RCA obstruction that leads to MI
II, III, aVF
what to administer to someone having STEMI at bedside of hospital
MONA (morphine, O2, NTG, Aspirin)
biomarkers that will be increased in STEMI
Troponin I
CK-MB
biomarker for re-infarction
CK-MB
sign of acute MI (pulmonary edema)
top and bottom
top: anterior
bottom: posterior
type of MI w/ ischemic necrosis of endo, myo, and epicardium
Transmural
type of MI w/ ischemic necrosis of endo and subendocardial myocardium
Nontransmural
most dangerous MI
Transmural
normal myocyte
how to distinguish b/t acute MI or myocarditis
acute MI: red/dead some neutrophils
myocarditis: some red/dead, lots of neutrophils, pt. is FEBRILE
irreversible myocyte injury
neutrophils seen on R
irreversible myocyte injury
granulation tissue on L and scar on R
increased thickness of L ventricle due to HTN, aortic valve stenosis, hypertrophic cardiomyopathy
L ventricular hypertrophy
LV hypertrophy
more muscle= _____amplitude of QRS complex
greater
increased thickness of RV due to severe lung disease and valve defects/infections/congenital disorders
RV hypertrophy
RV hypertrophy (R should never be size of L)
large QRS amplitude seen in V1
RV hypertrophy
narrowing of artery due to atherosclerosis
CAD
due to vessel damage caused by chronic inflammation reactive to buildup of cholesterol and plaques in walls of arteries
CAD
atheroma
thrombus
best Rx for CAD
combination therapy of diet/exercise + meds
MI from LAD occlusion seen in what leads
V1-V4
MI from occlusion of LCA seen in what leads
I, aVL, V5, V6
transmural infarct
myocardial rupture
myocardial fibrosis from ventricular aneurysm
subendocardial infarct
MI necrosis; <24 hrs
acute inflammation; days
granulation tissue; 3 dys-weeks
fibrosis; months
MI from LAD
L arrow: necrosis
R arrow: inflammation