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Pharmacology > Indocrine Drugs > Flashcards

Indocrine Drugs Flashcards

1
Q

master gland, common site of tumors

A

Pituitary Gland

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2
Q

FSH
LH
Growth Hormone

A

Anterior Pituitary

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3
Q

Decreased GH

A

Dwarfism

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4
Q

-Somatropin
*do not inject if epiphysis is closed
SQ injection; anabolic – builds up
SE: fluid retention and myalgia
-Anabolic substance nandroxone and oxandrolone
stimulates protein synthesis, inc. cartilage, and bone growth
May have cardiac arrest

A

Drugs for Dwarfism

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5
Q

Increased GH if open epiphysis

A

Gigantism

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6
Q

Bromocriptine (Parlodel)

A

Dopamine agonists

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7
Q

Pegvisomant (Somavert)

A

GH receptor antagonists

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8
Q

Increased GH if closed epiphysis
Prognathism enlarged jaw

A

Acromegaly

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9
Q

Thyroid glant to produce T3 and T4 Needs iodine to produce
T3 -Triiodothyronine, also known as T₃, is a thyroid hormone. It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate.
T4 -Thyroxine (referred to as T4) is a major player in your endocrine system. It is responsible for your metabolism, mood, and body temperature

A

TSH (Thyroid stimulating hormone)

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10
Q

Severe Hypothyroidism
Mentally retarded

A

Myxedema

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11
Q

Severe Hypothyroidism
Mentally retarded

A

Myxedema

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12
Q

Children without Thyroid gland
Mentally retarded

A

Cretinism

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13
Q

Levothyroxine (Synthroid) – T4
Liothyronine (Cytomel) – T3
Liotrix (Euthyroid) – combination

A

Thyroid hormones

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14
Q

no frequent swallowing is at the neck; bleeding at neck
Shrink and reduce vascularity of the thyroid gland before thyroidectomy with SSKI/Lugol’s solution

A

Thyroidectomy

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15
Q

targets adrenal glands: cortex and medulla
Cortex
Glucocorticoids (Cortisol/Steroids)
Catabolic- breakdown CHON,CHO, Fats -> high glucose -> CHON breakdown (fluid shifting) -> edema, muscle wasting, osteoporosis,stretch marks,immunosuppressant (antibodies are made of proteins) -> fat breakdown ->central (truncal) obesity
Buffalo hump
Anabolic steroids – pure androgen; used by athletes

A

ACTH (adrenocorticotropic hormone)

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16
Q

Retains Na and water

A

Mineralocorticoids (Aldosterone)

17
Q

Hirsutism
Stimulation of sebaceous glands

A

Androgens (secondary male characteristics)

18
Q

High GMA/excess of the hormone cortisol.
High water and sodium; low potassium
SIADH (Syndrome of inappropriate antidiuretic hormone secretion)– no high sodium
If secondary to medicine –Cushing’s Syndrome

A

Cushing’s Disease

19
Q

Low GMA/inadequate production of the steroid hormones cortisol and aldosterone
Steroids
Addisonian(Adrenal)Crisis – do not stop abruptly
Taken with meals

A

Addison’s

20
Q

Pheochromocytoma – more E,NE due to tumor
Antihypertensive
Remove adrenal gland (adrenalectomy)

A

Medulla: Epinephrine, Norepinephrine

21
Q

PTU(Propythiouracil)
Prevent the formation of thyroid hormone
Not for pregnant women – cretinism
SE: Aggranulocytosis – monitor for signs of
infection
Tapazole (Methimazole)
Tonsillectomy – frequent swallowing
Posterior Pituitary
Oxytocin
ADH (vasopressin) – water retention/reabsorption
Inc. ADH – SIADH
High BP, edema
Fluid restriction
Diuretics
Dilutional hyponatremia3% NaCl
Dec. ADH – Diabetes Insipidus
Polyuria
Dehydration -> polydipsia
Fluid Deprivation Test
Even if deprived for 10 hours, urinate
1kilo – 1 L
Give vasopressin (Pitressin, Lypressin; nasal, Desmopressin: oral IV, nasal spray)

A

ANTI THYROID MEDICATIONS

22
Q

Type 1 – No Insulin
Type 2 – With less functional insulin
1. Rapid Acting: Lispor (Humalog)
a. 10-15 mins, 1 hour peak, duration 3 hours
2. Short acting: Regular
a. O 30 mins-1hr P 2-4 hrs,D 6-8 hrs
3. Intermediate acting: NPH and Lente
a. O 2-4 hrs P 8-12 D 12-16 hrs
4. Long acting insulin
5. Glargine (Lantus) – no peak; no hypoglycemia; 24 hour insulin

A

INSULIN

23
Q

Peak action is the time when you experience hypoglycemia

A

Regular and NPH

24
Q

is SQ and IV
Regular first. Clear then cloudy. Rotate sites (1 in apart) to prevent lipodystrophy

A

Regular insulin

25
Q

Oral Antidiabetic – must have functioning beta cells (Type 2)
Administer all insulin SQ, only regular for IV
DKA – Type 1; HHNKS – Type 2
Abdomen fastest route, then arms
Do not inject cold insulin (lipodystrophy)
Store in room temp (1 month), refrigerator (3 months)

A

DO NOT MIX LANTUS

26
Q

Pump that secretes insulin continuously
Mimics pancreatic functioning
Needle is changed only 3 days; embedded; not changing everyday

A

INSULIN PUMP

Pharmacology (6 decks)

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