Central Nervous System Drugs

Question 1

Drugs agents that act on the brain and spinal cord are used for medical and nonmedical purposes

Answer 1

Central nervous system (CNS)

Question 2

The CNS contains how many compounds that serve as neurotransmitters?

Answer 2

21

Question 3

Neurotransmitters of the CNS

Answer 3

Monoamines
Amino Acids
Purines
Opioid Peptides
Nonopioid Peptides
Others like
Acetylcholine histamine

Question 4

Certain drugs used in psychiatry antipsychotics and antidepressants must be taken for several weeks before full therapeutic effects develop.

Answer 4

Increased Therapeutic Effects

Question 5

When CNS drugs are taken long term, the intensity of side effects may decrease (while therapeutic effects remain undiminished).

Answer 5

Decreased Side Effect

Question 6

A decreased response occurring in the course of prolonged drug use

Answer 6

Tolerance

Question 7

A state in which abrupt discontinuation of drug use will precipitate a withdrawal syndrome

Answer 7

Physical dependence

Question 8

Can protect the CNS from toxic substances, but can also block entry of medicines into the CNS.

Answer 8

Blood-brain barrier

Question 9

Are usually indicated for specific psychiatric disorders such as schizophrenia delusional disorders, bipolar disorder, depressive psychoses and drug induced psychoses

Answer 9

Psychotherapeutics

Question 10

Antipsychotics

Answer 10

-First Generation Antipsychotics (GGAs)
-Second Generation Antipsychotics (SGAs)

Question 11

Also called conventional antipsychotics that blocks receptors for dopamine in the CNS and causes serious movement disorders called EPS

Answer 11

First Generation Antipsychotics (FGAs)

Question 12

Also called atypical antipsychotics that moderately blocks dopamine but stronger blocking of receptors for serotonin and it decrease blocking of dopamine that leads to lesser risk of EPS

Answer 12

-Second Generation Antipsychotics (SGAs)

Question 13

Chronic psychotic illness characterized by disordered thinking and reduced ability to comprehend reality

Answer 13

Schizophrenia

Question 14

Principal symptoms are depressed and loss of pleasure or interest in all or nearly all of one’s usual activities and past times that persist for longer than 2 months or are characterized by marked functional impairment, morbid preoccupation with worthlessness, suicidal ideation or psychotic symptoms or psychomotor retardation.

Answer 14

Major depression

Question 15

5 Major Antidepressants

Answer 15

-Tricyclic antidepressants
-Selective serotonin reuptake inhibitors
-serotonin and norepinephrine reuptake inhibitors
-Monoamine oxidase inhibitors
-Atypical antidepressants

Question 16

Characterized with terms such as fear, apprehension, dread, and uneasiness.

Answer 16

Anxiety

Question 17

First choice drug for anxiety

Answer 17

Benzodiazepines

Question 18

Symptom of many conditions and is often what prompts patients to seek medical help

Answer 18

Pain

Question 19

Pain which occurs immediately on tissue damage

Answer 19

Productive pain

Question 20

Even though this is often caused by tissue injury, one has minimal control over this type of pain

Answer 20

Nonproductive pain

Question 21

Caused by activity in neutral pathways in response to potentially tissue- damaging stimuli

Answer 21

Neuropathic Pain