indirect sympathomimetics Flashcards
1
Q
what are 3 agents?
A
amphetamine, cocaine, ephedrine
2
Q
amphetamine mechanism?
A
reuptake inhibitor, also release stored catecholamines
3
Q
cocaine mechanism?
A
reuptake inhibitor
4
Q
ephedrine mechanism?
A
releases stored catecholamines
5
Q
amphetamine use?
A
narcolepsy, obesity, ADHD
6
Q
narcolepsy, obesity, ADHD what drug?
A
amphetamine
7
Q
cocaine effect?
A
vasoconstriction and local anesthesia
causes mydriasis with intact sympathetic system –> used to confirm Horner syndrome
8
Q
ephedrine application?
A
nasal decongestant (pseudoefedrine), urinary incontinence, hypotension
9
Q
what happens when given beta blockers in cocaine overdose?
A
unopposed alpha 1 effect –> high increase in BP and coronary vasospasm –> MI, prinzmetal angina
