cholinomimetics

Question 1

Betanechol. direct or indirect?

Answer 1

direct

Question 2

Carbachol. direct or indirect?

Answer 2

direct

Question 3

Metacholine. direct or indirect?

Answer 3

direct

Question 4

Pilocarpine. direct or indirect?

Answer 4

direct

Question 5

Donepezil. direct or indirect?

Answer 5

indirect

Question 6

rivastigmine. direct or indirect?

Answer 6

indirect

Question 7

galantamine. direct or indirect?

Answer 7

indirect

Question 8

edrophonium. direct or indirect?

Answer 8

indirect

Question 9

neostigmine. direct or indirect?

Answer 9

indirect

Question 10

physostigmine. direct or indirect?

Answer 10

indirect

Question 11

pyridostigmine. direct or indirect?

Answer 11

indirect

Question 12

Donepezil/rivastigmine/galantamine. CNS?

Answer 12

cross BBB

Question 13

Edrophonium. CNS?

Answer 13

does not cross BBB

Question 14

Neostigmine. CNS?

Answer 14

does not cross BBB

Question 15

Physostigmine. CNS?

Answer 15

cross BBB

Question 16

Pyridostigmine. CNS?

Answer 16

does not cross BBB

Question 17

Betanechol. What receptors?

Answer 17

only M (all)

Question 18

Carbachol. Whart receptors?

Answer 18

M and N

Question 19

Metacholine. what receptors?

Answer 19

M>N

Question 20

Pilocarpine. what receptors?

Answer 20

M

Question 21

Acetylcholine. direct or indirect?

Answer 21

direct

Question 22

Acetylcholine. what receptors?

Answer 22

both M and N

Question 23

What for Alzheimer 1st line?

Answer 23

Donepezil/rivastigmine/galantamine

Question 24

Postoperative and neurogenic ileus and urinary retention?

Answer 24

Neostigmine

Question 25

Myastenia gravis. more often and less often?

Answer 25

more often pyridostigmine
less often neostigmine

Question 26

NMJ reversal?

Answer 26

neostigmine

Question 27

Antidote for anticholinergic toxicity (atropine)?

Answer 27

Physostigmine

Question 28

Which drug induces muscle strenght?

Answer 28

pyridostigmine

Question 29

which drug used with glycopyrolate/hyoscyamine/propantheline to control effect?

Answer 29

pyridostigmine

Question 30

what is tertiary amines (lipophilic)?

Answer 30

cross BBB

Question 31

what is quaternary amines (hydrophilic)?

Answer 31

does not cross BBB

Question 32

tertiary - reverse both central and peripheral
quaternary - reverse only peripheral

Answer 32

.

Question 33

Which drug stimulates M receptors in airways when inhaled?

Answer 33

metacholine

Question 34

metacholine application?

Answer 34

chalenge test for diagnosis of asthma

Question 35

which drug ,,copy of ACh”, but resistant to AChE?

Answer 35

Carbachol

Question 36

Carbachol application?

Answer 36

constricts pupil and relieves intraocular pressure in open-angle glaucoma

Question 37

chalenge test for diagnosis of asthma?

Answer 37

metacholine

Question 38

constricts pupil and relieves intraocular pressure in open-angle glaucoma?

Answer 38

Carbachol

Question 39

Which durg (direct) artivates bladder and bowel smooth muscles?

Answer 39

betanechol

Question 40

betanechol application?

Answer 40

urinary retention;
ileus (post-op/neurologic).

Question 41

urinary retention;
ileus (post-op/neurologic)
What drug?

Answer 41

direct - betanechol
indirect - neostigmine

Question 42

potent stimulator of sweat/tears/saliva?

Answer 42

pilocarpine

Question 43

contracts ciliary muscle –> used in open-angle glaucoma)?

Answer 43

pilocarpine

Question 44

contracts sphincter muscle –> used in closed-angle glaucoma)?

Answer 44

pilocarpine

Question 45

which direct drug cross BBB (tertiary amine)?

Answer 45

pilocarpine

Question 46

which drug used in xerostomia (sjogren)?

Answer 46

pilocarpine