in class questions Flashcards
1
Q
What outcomes are currently used to Diagnose prediabetes and type 2
A
- oral glucose test
-fasting plasma glucose
-GLycated hemoglobin A1C
2
Q
what is the major defect fro insulin resistance in sketal muscle
A
impared glucose uptake
3
Q
what are the ,main metabolic consequences of insulin resistance in the adipose tissue
A
reduced lipolysis
reduced glucose uptake
4
Q
why does blood glucose increase when the liver is IR
A
- insulin is less effective at shutting off gluconeogensis
- insulin is less effective at shutting off glycogenolysis
5
Q
What is the best technique to directly measure muscle insulin sensitivty
A
hyperinsulinemic-euglycemic clamp
6
Q
which test would be the best for live insulin resistance
A
Fasting HOMA-IR score
7
Q
what is the correct order of Hyperglycemia, Hyperinsulinemia, IR in occurrence during the development of T2D
A
IR, hyperinsulinemia, Hyperglycemia
8
Q
A