Impaired Immune Function Diseases Flashcards
1
Q
What is the dysfunction of Chronic Granulomatous Disease?
A
Ineffective phagocytosis
2
Q
What is the dysfunction of Chediak Higashi Syndrome?
A
Impaired neutrophil function
fusion of primary granules = large lysosomes
3
Q
What is the dysfunction of DiGeorge Syndrome?
A
T Cell deficiency (absence of thymus)
4
Q
What is the dysfunction of HIV?
A
Decreased CD4+ cells (T helper)
Decreased T helper:T regulatory ratio (CD4:CD8 Ratio)
Decreased T cell proliferation
5
Q
What is the dysfunction of Wiskott-Aldrich Syndrome?
A
Partial combined immunodeficiency
6
Q
What is the dysfunction of Severe combined immunodeficiency disease (SCID)?
A
Complete or marked deficiency of T and B lymphocytes
