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ASCP Immunology > Autoimmune Diseases > Flashcards

Autoimmune Diseases Flashcards

1
Q

In Grave’s Disease, what is the auto-antibody directed against?

A

Autoantibody (IgG) that is directed towards the myelin sheath of nerves or myelin basic protein.

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2
Q

What are lab findings of MS?

A

IgG bands in CSF but not in serum

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3
Q

What is Grave’s Disease?

A

A form of hyperthyroidism

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4
Q

What are lab findings of Grave’s Disease?

A

Low TSH
Elevated T3 and T4
Elevated thyroid antibodies

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5
Q

In Hashimoto’s Thyroiditis, what is the auto-antibody directed against?

A

Thyroglobulin

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6
Q

In Goodpasture’s disease, what is the auto-antibody directed against?

A

Basement membrane of kidney and lungs

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7
Q

In Myasthenia Gravis, what is the auto-antibody directed against?

A

Acetylcholine receptors at neuromuscular junctions

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8
Q

In RA, what is the auto-antibody directed against?

A

The IgG fc region

RF factor is a 19s anti-IgM autoantibody

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9
Q

In Sjogren’s Syndrome, what is the auto-antibody directed against?

A

Salivary Duct / Tear Duct

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ASCP Immunology (16 decks)

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