Immunotherapy Flashcards
1
Q
Nivolumab
A
PD-1/PD-L1 Inhibitor
- Targets Lung
- Prevents binding to PD-L1 or PD-L2 receptor
–> Prevents Down regulation of T Cell
2
Q
Pembrolizumab
A
PD-1/PD-L1 Inhibitor
- Targets Lung
- Prevents binding to PD-L1 or PD-L2 receptor
–> Prevents Down regulation of T Cell
3
Q
Atezolizumab
A
PD-1/PD-L1 Inhibitor
- Targets Lung
- Prevents binding to PD-L1 or PD-L2 receptor
–> Prevents Down regulation of T Cell
4
Q
Durvalumab
A
PD-1/PD-L1 Inhibitor
- Targets Several
- Prevents binding to PD-L1 or PD-L2 receptor
–> Prevents Down regulation of T Cell
5
Q
Ipilimumab
A
CTLA Inhibitor
- Target Several
- Prevents binding to B7 protein
–> Prevents Down regulation of T Cell
6
Q
Neoantigen
A
Delivery Strategies
- DNA/mRNA
- SLPs
- Pulsed DCs
- Nanovaccines