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BC Paeds Exam > Immunology > Flashcards

Immunology Flashcards

1
Q

Hypogammaglobulinaemia leads to what kind of infections?

Name 3 common bugs

A

Recurrent sino-pulmonary infections

S pneumoniae, H influenzae

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2
Q

Recurrent peri-anal abscesses are common in…

A

HyperIgE

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3
Q

What Immunoglobulin is lost in PLE?

A

IgG

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4
Q

Which IG is transferred in breast milk?

A

IgA

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5
Q

Which IG is transferred accross placenta?

A

IgG

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6
Q

HyperIgE

  1. 2 common infectious pathogens
  2. Th and IL involved
A
  1. Staph: Skin (abscesses) and respiratory
    Candida: Mucocutaneous Candidiasis
  2. Th17. IL-10
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7
Q

Hyper IgE IG Profile

A 
\+++++ High Serum IgE
High IgD
Normal IgG, IgA, IgM
Eosinophilia
STAT3 mutation (JAK-STAT)
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BC Paeds Exam (14 decks)

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